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肺动脉、支气管动 脉双期CTA成像在咯 血介入栓塞治疗中 的应用价值

作者:李旭丰 杨海南 陈志远 邓娇娇

所属单位:广州医科大学附属第二医院放射科 (广东 广州 511447)

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摘要

目的 探讨肺动脉、支气管动脉 双期CTA成像在咯血介入栓塞治疗中的应 用价值。方法 选取我院2014年至2016年 期间因咯血行介入栓塞治疗患者35例进行 分析,全部患者均接受术前两期CTA扫描 和介入栓塞治疗,在CTA上进行多平面重 建(MPR)、最大密度投影(MIP)、容积再现 (VR)等处理,确定供血动脉。以数字减 影血管造影(DSA)为金标准,对两组数据 进行对比,评价肺动脉、支气管动脉CTA 双期扫描对肺咯血病变的影像表现、咯血 的不同病变血管的检出符合率(敏感性)、 咯血责任血管数量的符合率(特异性)等。 结果 肺动脉、支气管动脉CTA双期扫描成 像能较充分的观察肺部的基本病变,以及 体肺动脉分流征象、肺动脉源性出血的病 变,其对病变血管的检出具有较高的敏感 性(79.7%)和特异性(91.4%),但对较细 分支水平的体肺动脉分流、对较细小的肺 外体动脉侧枝的检出相对较差。结论 肺 动脉、支气管动脉CTA双期扫描成像在咯 血介入栓塞治疗中能有效发现体动脉或肺 动脉源性出血的病变,对咯血责任血管的 检出具有较高的敏感性和特异性,同时, 能够在术前较充分了解病变血管的开口形 态、位置等,可以作为常规的术前检查进 行运用,从而缩短手术时间,提高手术止 血成功率。

Objective To study the value of double phase CTA scan of pulmonary artery and bronchial artery in the treatment of hemoptysis. Methods From 2014 to 2016, 35 patients with hemoptysis by interventional embolization were selected. All patients were underwented by CTA scan and interventional embolization before operation, Multi planar reconstruction (MPR), Maximum intensity projection(MIP), volume rendering (VR) and so on were performed on CTA, and multi angle rotation were combined to determine the feeding artery. The CTA examination of the blood vessels was confirmed by DSA and DSA as the gold standard. The data of the two groups were compared, to evaluate the imaging features of pulmonary artery and bronchial artery double phase CTA scan in the diagnosis of Pulmonary Hemoptysis, the detection coincidence rate (sensitivity) of different pathological changes of hemoptysis, the coincidence rate of the number of blood vessels (specificity) of hemoptysis and so on. Results The basic pathological changes of pulmonary artery and bronchial artery CTA double phase scanning imaging could fully observe the lungs, and pulmonary artery shunt signs, pulmonary artery source bleeding lesions. It had a high sensitivity (79.7%) and specificity (91.4%) for the detection of diseased vessels, but the result of inspect about body of pulmonary artery to the thin branch level of shunt, small pulmonary collateral arteries in the body was relatively poor. Conclusion The pulmonary artery and bronchial artery CTA double phase scanning imaging in hemoptysis interventional embolization could effectively found artery or pulmonary source bleeding lesions, it had high sensitivity and specificity for the detection of the blood vessel of hemoptysis, at the same time, it could be able to fully understand the opening and shape of the diseased vessels before operation, it could be used as a routine preoperative examination, so as to shorten the operation time and improve the surgical success rate of hemostasis, and to provide important guidance for surgical treatment.

【关键词】肺动脉;支气管动脉;CTA; DSA;栓塞治疗

【中图分类号】R73;R54

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.08.022

前言

咯血是指气管、支气管及肺组织等喉部以下的呼吸器官出血,是 临床上常见的疾病,如果出血量较大,可能会威胁到生命安全[1]。介 入栓塞是治疗大咯血的安全有效的方法,而在治疗之前对于责任血管 的确认是治疗成功的关键[2],数字减影血管造影(DSA)是活体气管动脉 检查的金标准,但这种方法具有明显的创伤,费用也比较高[3]。CT血 管造影(CTA)是后续发展出现的一种检查方法,并逐渐在临床上推广应 用,有逐渐代替DSA的趋势。本研究针对CTA扫描的方法进行分析,并 与DSA进行比较,详细阐述双期CTA扫描在大咯血患者的检查效果和对 于介入手术的指导作用,从而为相关研究提供参考。