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论著-头颈部

22例滑膜肉瘤的影 像学分析

作者:刘培培1,2 陈高红1 吴 磊1,2 徐 凯1

所属单位:1.徐州医学院 (江苏 徐州 221004) 2.徐州医学院附属医院影像科 (江苏 徐州 221006)

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摘要

目的 分析滑膜肉瘤的CT和MRI表 现及其相关临床病理特征,探讨CT和MRI 对滑膜肉瘤的诊断价值。方法 回顾性分 析22例经手术病理证实的滑膜肉瘤患者的 临床和影像学资料。结果 肿瘤多位于四 肢关节附近的深部软组织内,呈“钻孔样 或包绕样”生长趋势;病灶呈圆形或卵圆 形,部分可有分叶,轮廓多较清晰。肿 瘤体积一般较大,22例病灶最大直径为 3.1cm-13.4cm,平均7.1cm。由于常合并 坏死、囊变、出血等,病灶密度或信号多 不均匀。CT平扫多呈等或稍低密度的软组 织肿块,6例病灶内可见坏死区,2例病灶 合并有钙化。MRI平扫肿瘤实性部分T1WI 多呈等或稍低信号,5例病灶内部TIWI可 见高信号区,提示合并出血;T2WI病灶信 号较混杂,部分病灶内部可见分隔样低信 号影;压脂序列肿瘤显示较好,呈明显高 信号;3例伴有邻近的骨质破坏。增强CT 和MRI表现相仿,多呈明显不均匀强化。 结论 滑膜肉瘤的影像学表现具有一定特 征性,CT和MRI综合评价有助于提高滑膜 肉瘤的的诊断准确性,确诊仍需依靠病理 学检查。

Objective According to the imaging findings and its related clinical and pathologic characters of synovial sarcoma (SS), to explore the diagnostic value of the CT and MRI. Methods The Clinical and imaging data of 22 SS confirmed by pathology were retrospectively analyzed. Results Most of the SS located in the deep soft tissue near the extremities and joints, showing "drilling or encircling -like" growth trend. They were generally round, oval or lobulated in shape and well-defined. The tumors were generally larger, the maximum diameter of the 22 cases was 3.1cm-13.4cm and the average was 7.1cm. The density or signal was heterogeneous as the tumors were often with necrosis or cystic areas and hemorrhage. On CT, most lesions appeared soft-tissue mass with attenuation similar to or slightly lower than that of muscle, 6 cases with the necrosis aera and 2 cases with calcification inside it. On T1WI of the MRI, the solid part of the tumors usually presented iso- or hypo-intense. 5 cases showed patch hyperintense area, which suggested the hemorrhage. On T2WI, the signal was heterogeneous, some cases with hypointense septa among the lesions. The tumors were obviously high signal in the fat suppression sequence. 3 cases appeared destruction of the adjacent bone. After contrast, the performance of CT and MRI was similar, most of the tumors showed obviously heterogeneous enhancement. Conclusion SS has some special imaging manifestation, combining CT and MRI can improve the diagnostic accuracy of SS, however, pathology is still mandatory to confirm the diagnosis.

【关键词】滑膜肉瘤;体层摄影术;X线 计算机;磁共振成像

【中图分类号】R738.5

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.07.040

前言

滑膜肉瘤起源于具有向滑膜组织分化潜能的间叶细胞,是一种较 少见的软组织恶性肿瘤。由于其发病率低,且临床体征及影像表现多 变,为了进一步提高对该肿瘤的认识水平,本文回顾性分析了经手术 病理证实的22例滑膜肉瘤患者的影像学和临床病理资料,并结合文 献,探讨其影像表现及相关诊断要点。