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核磁共振联合超声成像在原发性小卵巢癌诊断中的应用研究*

作者:朱朝选

所属单位:河南省许昌市人民医院(河南 许昌 461000)

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摘要

目的 探究超声(US)联合核磁共 振成像(MRI)在原发性小卵巢癌诊断中的 临床应用价值。方法 选取70例原发性小 卵巢癌患者为研究对象,术前均分别行 US、MRI检查,以术后病理结果作为金标 准纳入研究对象的临床病历资料及影像 学资料,并进行整理和分析。结果 70例 患者各病理类型诊断合计MRI×US准确率 94.29%显著高于US、MRI准确率70.00%、 81.43%(P<0.05)。US表现肿瘤多呈囊实 性,囊壁与隔厚薄不均,大网膜不均匀增 厚,并有结节样改变。而彩色血流信号以 Ⅲ级为主,彩色血流肿块内有高速低阻的 动脉血流动,其多分布于肿块实质,血管 分布呈条状,树枝状,团状等多种形态。 MRI表现肿瘤多为囊性肿块或囊实性肿 块,囊壁光滑,肿瘤直径44.9-365.7mm; MRI平扫T1WI呈低信号或低、等信号, T2WI呈高、略高信号,信号不均匀,呈混 杂信号,DWI呈不均匀高、低混杂信号; 动态增强扫描可见厚薄不均的囊壁且囊内 片状阴影、囊壁、间隔及结节较明显强 化,实性部分强化明显。结论 US联合MRI 诊断原发性小卵巢癌准确率高,且二者影 像学特征明显,互为补充,联合诊断对原 发性小卵巢癌的防治有重要参考价值。

Objective To explore the clinical value of ultrasound (US) combined with magnetic resonance imaging (MRI) in the diagnosis of primary small ovarian cancer. Methods Seventy patients with primary small ovarian cancer were selected as study subjects. US and MRI were performed before operation. With postoperative pathological results as the golden standard, the clinical records and imaging data of the patients were included in the study and were analyzed. Results The total MRI×US accuracy rate in the diagnosis of all pathological types in 70 patients (94.29%) was significantly higher than that of US (70.00%) and MRI (81.43%) (P<0.05). US showed that most of the tumors were cystic, cystic wall and septum were uneven in thickness, greater omental were irregular thickened with nodular changes. The colorful blood flow signal mainly was grade III. There was high speed and low resistance artery blood flow in the masses with colorful blood flow, most of which were distributed in the parenchyma, and the distribution of blood vessels was strip, dendritic, mass and in other forms. MRI showed that the tumors were mostly cystic masses or cystic solid masses, the wall was smooth, and the tumor diameter was 44.9-365.7mm, MRI plain scan showed low signal or low and equal signal on T1WI, high or slightly high signal on T2WI. The signal was not uniform, manifesting as mixed signal. There was inhomogeneous high and low mixed signal on DWI. Dynamic contrast-enhanced scan showed that there were uneven thickness of the cystic wall and patchy shadows in cysts, cystic wall, septum and nodules were obviously enhanced, and the solid parts were enhanced obviously. Conclusion The accuracy rate of US combined with MRI in the diagnosis of primary small ovarian cancer is high, and imaging features of the two are obvious, and complement each other. The combined diagnosis is of great reference value in the prevention and treatment of primary small ovarian cancer.

【关键词】US;MRI;原发性小卵巢癌; 临床诊断

【中图分类号】R737.31

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.07.036

前言

原发性小卵巢癌在女性常见恶性肿瘤中占2.4%~6.5%,在女性生 殖系统癌瘤仅次于宫颈癌、宫体癌,其临床发病率呈逐年上升的趋 势,严重影响女性的身心健康和生存质量。虽然近几年来,医疗技术 的发展促使原发性小卵巢癌的临床防治取得了一定的进步,但原发性 小卵巢癌患者往往因早期缺乏典型症状难以引起重视,加之早期病变 不易被一般辅助检查发现和诊断,因此多数女性患者发病确诊时已属 晚期,进而耽误最佳治疗时机和错过最佳治疗方案[1]。近年来,不断 有研究报道US、MRI联合应用对女性肿瘤疾病如宫颈癌、乳腺癌等的诊 断具有重要价值[2],而目前部分基层医院单一的临床辅助诊断手段极 易导致原发性小卵巢癌的误诊、漏诊。本文分析近年来我院收治的70 例患者的临床影像学资料,探究US联合MRI在原发性小卵巢癌诊断中的 临床应用。现报告如下。