简体中文

论著-头颈部

不同危险度胃底间质瘤的CT征象及CT定量分析的临床意义

作者:周 刚1 曹 中2 熊永发1 江 鹏1 牟东景1 樊 斌1

所属单位:1.湖北黄冈市中心医院影像科 (湖北 黄冈 438000) 2.湖北黄冈市中心医院病理科 (湖北 黄冈 438000)

PDF

摘要

目的 通过观察不同危险度胃底 间质瘤(GIST)CT征象,分析MSCT对其定 位、危险度分级判断的临床意义。方法 以本院2013年2月-2016年1月经病理学证 实的60例胃底间质瘤患者为研究对象,根 据病理结果将其分为低度危险、中度危 险、高度危险三个等级,观察比较不同 危险度患者CT征象及CT值。结果 病理危 险度分级:低度危险、中度危险、高度 危险分别为30例、17例、13例。低度危 险、中度危险、高度危险GIST患者在肿 瘤最大径、密度、形态、肿瘤血管显示 方面比较差异有统计学意义(P<0.05)。 不同危险度GIST患者在发病部位、生长 方式、强化程度上比较差异无统计学意 义(P>0.05)。各危险度GIST患者平扫、 三期强化CT值比较差异有统计学意义(P <0.05)。结论 不同危险度胃底间质瘤CT 征象存在典型差异,从肿瘤最大径、密 度、形态、肿瘤血管显示上有助于GIST危 险度分级,为其临床治疗方案制定及预后 评估提供依据。

Objective To analyze the clinical significance of MSCT in positioning and judgment of risk classification through observing the CT findings of different risks of gastrointestinal stromal tumors (GIST). Methods 60 patients with GIST confirmed by pathology in our hospital between February 2013 and January 2016 were selected as the study objects. According to the pathological results, they were divided into the low risk, moderate risk, high risk of three levels. The CT findings of different risks of patients and CT values were observed and compared. Results In terms of pathological risk classification, the number of cases of low risk, moderate risk and high risk were 30, 17 and 13. The differences in displaying tumor size, density, shape and tumor blood vessels between patients with low risk, moderate risk and high risk GIST were statistically significant (P<0.05). There was no significant difference in pathogenic site, growth pattern and degree of enhancement between patients with different risks of GIST (P>0.05). There were significant differences in plain scan and three-phase enhanced CT values between patients with different risks of GIST (P<0.05). Conclusion There exist typical differences in CT findings of different risks of DIST. The display of tumor size, density, shape and tumor blood vessels contributes to risk classification, which provides the basis for the development of clinical treatment and evaluation of prognosis.

【关键词】胃底间质瘤;危险度分级;CT 征象

【中图分类号】R322.4+4

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.07.032

前言

胃肠道间质瘤(Gastrointestinal Stromal Tumor,GIST)具有非定 向分化、潜在恶性病变特点,不同危险度分级患者预后不一[1]。且临 床实践表明术前肿瘤危险度分级判断在很大程度上直接关系到手术方 案制定及其预后,为此干预前准确判断GIST危险度分级十分必要。从 病理学方面来说,主要依据肿瘤大小、部位、有丝分裂等判断GIST性 质,但受病理取材影响,难以准确分级,需从肿瘤形态、密度等方面 综合分析,为此需借助多层螺旋CT(MSCT)辅助判断[2]。为了探讨MSCT 征象对胃底间质瘤危险度分级的诊断价值,本研究对2013年2月~2016 年1月经病理学证实的60例GIST患者MSCT影像学表现进行回顾性分析。 现报告如下。