目的 探讨MRI在鉴别诊断乳腺良 恶性病变中的临床价值。方法 选取我院 收治的80乳腺病变患者的临床资料，均接 受MRI检查，以手术病理诊断为金标准， 统计MRI对良恶性病变的敏感性、特异性 及准确性，观察和记录良恶性病变病灶形 态和边缘情况及强化和受累情况，并统计 良恶性病变早期增强率、最大增强率及相 对最大增强率。结果 80例患者经手术病 理诊断为良性病变者46例，恶性病变者34 例，MRI对乳腺病变良恶性鉴别诊断的敏 感度为90.48%，特异性为88.24%，准确性 为85.00%。恶性乳腺病变形态不规则、边 缘不光滑、毛刺、结节或肿块样强化及周 围组织受累方面占比显著高于良性病变， 差异均有统计学意义(P＜0.01)。恶性乳 腺病变MRI早期增强率、最大增强率及相 对最大增强率均明显高于良性病变，差异 均有统计学意义(P＜0.01)。结论 乳腺 良、恶性病变MRI影像学特征差异明显， 尤其是恶性病变增强率明显较高，故MRI 鉴别诊断乳腺良恶性病变具有较高的敏感 度、特异性和准确性。

Objective To investigate the clinical value of MRI in differential diagnosis of benign and malignant breast lesions. Methods The clinical data of 80 patients with breast lesions in our hospital were examined by MRI. With the pathological diagnosis as the golden standard, the sensitivity, specificity and accuracy of MRI in the diagnosis of benign and malignant lesions were statistically analyzed. The shapes, edges, enhancement and involvementof benign and malignant lesions were observed and recorded. The early enhancement rate, the maximum enhancement rate and the maximum relative enhancement rate of benignand malignant lesions were also statistically analyzed. Results Among 80 cases, there were 46 cases with benign lesions and 34 cases with malignant lesions confirmed by surgery and pathology. The sensitivity, specificity and accuracy of MRI in the differential diagnosisof benign and malignant breast lesions were 90.48%, 88.24% and 85.00% respectively. The proportions of irregular shape, rough edges, burr, nodule or mass like enhancementand involvement of surrounding tissues of malignant breast lesions were significantly higher than those of benign lesions(P<0.01).The early enhancement rate, the maximum enhancement rate and the maximum relative enhancement rate of malignant breast lesions were significantly higher than those of benign lesions (P<0.01). Conclusion MRI imaging features of benign and malignant breast lesions are significantly different, especially the enhancement rate of malignant lesions is significantly higher. Thus, MRI is with high sensitivity, specificity and accuracy in the differential diagnosis of benign and malignant breast lesions.