目的 探讨肺部磨玻璃结节的 HRCT征象及其病理分期的关系。方法 回 顾性分析从2014年5月至2016年5月行CT扫 描的78例肺部磨玻璃结节患者的术前CT图 像。所有病灶按病理结果分为：14例浸润 前病变(不典型腺瘤样增生(AAH)和原位 腺癌(AIS))、24例微浸润腺癌(MIA)和40 例浸润性腺癌(IAC)。对3组病灶的空泡 征、毛刺征、分叶征、支气管充气征及胸 膜凹陷征进行对比分析诊断浸润性腺癌的 界值。结果 浸润前病变与IAC间比较：毛 刺征、分叶征、胸膜凹陷征的差异有统计 学意义(P<0.05)；MIA与IAC间比较：胸膜 凹陷征的差异有统计学意义(P<0.05)；浸 润前病变与MIA间比较：毛刺征及胸膜凹 陷征的差异有统计学意义(P<0.05)。浸润 组(IAC)结节一般较无或微浸润组（浸润 前病变与MIA）边缘毛刺、分叶、内部空 泡及胸膜凹陷多见(P<0.05)。结论 肺磨 玻璃结节的HRCT征象与病理结果有一定的 相关性，分析上述影像征象有助于对术前 肺部磨玻璃结节进行鉴别诊断及分期。

Objective This study aimed to compare the high-resolution computed tomography (HRCT) image features of patients with Pulmonary ground-glass nodules (GGNs) with histopathology. Methods A total of 78 pulmonary GGNs cases resected between May 2014 and May 2016 were evaluated and pathologically classified as pre-invasive lesions (atypical adenomatous hyperplasia(AAH) and adenocarcinoma in situ(AIS),n=14), minimally invasive adenocarcinoma (MIA, n=24), invasive adenocarcinoma (IAC, n=40). The spiculation, lobulation, air-containing space, vacuole sign and pleural indentation on CT images were compared with pathological results to identify the features that helped distinguish between invasive group(IAC) and non-or minimally- invasive group(preinvasive lesions and MIA). Results There were statistically significant differences in lesion spiculation, lobulation, pleural indentation between preinvasive lesions and IAC (P<0.05). There were statistically significant differences in pleural indentation between MIA and IAC (P<0.05), there were statistically significant differences in spiculation and pleural indentation between preinvasive lesions and MIA (P<0.05), the more spiculations, lobulations, vacuole signs and pleural indentations were present in the invasive group than non- or minimally- invasive group (P<0.05). Conclusion HRCT manifestations of pulmonary ground-glass nodules has certain correlation with the pathological results, analysis the imaging performance helps to identify preoperative diagnosis．