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CT引导下射频消融治疗肺癌76例的影像学、并发症及存活情况分析

作者:蒋 明 胡鸿涛

所属单位:河南省安阳市肿瘤医院介入科(河南 安阳 455000)

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摘要

目的 分析CT引导下射频消融 治疗肺癌的影像学效果、并发症及存 活情况。方法 回顾性分析本院2013年 5月-2015年5月行CT引导下射频消融治 疗的76例肺癌的相关资料,观察比较射 频消融治疗前后影像学变化,并记录并 发症及随访1年存活率。结果 随访3个 月、6个月、12个月病灶局部控制率分 别为96.51%、93.02%、86.05%;治疗后 6个月肿瘤面积(13.26±3.14)cm2 ,CT值 (50.60±17.18)HU,均显著少于治疗前 的(11.52±4.82)cm2 、(35.74±12.35) HU,差异有统计学意义(P<0.05);术 中术后气胸发生率13.16%,发热发生率 17.10%,血痰发生率6.58%,无血胸等手 术相关严重并发症发生;1年无进展生存 率73.68%。结论 CT引导下射频消融治疗 肺癌效果好,并发症少,安全可行。

Objective To analyze the imaging effects, complications and survival of CT guided radiofrequency ablation for lung cancer. Methods The related data of 76 patients with lung cancer treated by CT guided radiofrequency ablation in our hospital during May 2013 to May 2015 were retrospectively analyzed. The imaging changes were observed and compared before and after radiofrequency ablation, and the complications and 1-year survival rate were recorded. Results In 3 months, 6 months and 12 months of follow-up, the local control rates of lesions were 96.51%, 93.02%, and 86.05% respectively. 6 months after treatment, the tumor area and CT value [(13.26±3.14) cm2 , (50.60±17.18) HU] were significantly smaller and lower than those before treatment [(11.52±4.82) cm2 , (35.74±12.35) HU] (P<0.05). The incidence rates of pneumothorax, fever and bloody sputum were 13.16%, 17.10% and 6.58%. There were no serious surgical complications related to hemothorax, and the 1 year progression free survival rate was 73.68%. Conclusion CT guided radiofrequency ablation is effective, safe and feasible in the treatment of lung cancer, and the complications are few.

【关键词】肺癌;CT引导;射频消融;影 像学表现

【中图分类号】R734.2;R445.3

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.07.010

前言

目前临床治疗肺癌仍首选外科手术,但受早期诊断无特异性、多 合并心肺并发症、高龄等多种因素影响,大多数肺癌患者失去最佳手 术时机或不耐受手术[1]。在这种形式下一种新的局部治疗方法—射频 消融在中晚期肺癌或转移癌中应用越来越多,它于CT等影像学引导下 通过射频热效应达到促瘤体凝固坏死的目的,能有效缩小或控制实体 瘤,具有微创、安全性高等特点[2-3]。本研究主要分析CT引导下射频消 融治疗肺癌的影像学、并发症及存活情况,以证明射频消融治疗肺癌 的可行性。