摘要
目的 研究宫颈癌CT灌注成像 分期与FIGO分期及病理分期的比较。方 法 采用GE Lightspeed UItra 16排多层 螺旋CT扫描仪对我院148例宫颈癌患者 进行增强扫描,图像传输至PACE系统并 进行多平面重建(MPR),得到冠状位、 矢状位、斜冠状位图像,比较CT分期、 FIGO分期及术后病理分期的差异。结 果 148例宫颈癌患者CT分期诊断Ⅰa期 27例、Ⅰb期41例、Ⅱa期28例、Ⅱb期 18例、Ⅲa期6例,分期正确120例,占 81.08%,其中7例CT、FIGO分期显示无病 变,漏诊率4.73%,后经术后脱落细胞学 检出,CT诊断过低分期8例,占5.41%, 过高分期20例,占13.51%,FIGO分期过 低分期31例,过高分期28例,诊断准确 率60.14%。结论 CT灌注成像分期准确 率高于FIGO分期,并可提供更多的病理 信息,可作为FIGO分期后的纠错检查措 施,CT对术前分期、手术方案选择及预 后有重要的指导意义。
Objective To compare CT perfusion imaging staging and FIGO staging and pathological staging of cervical carcinoma. Methods 148 patients with cervical carcinoma were scanned with GE Lightspeed UItra 16 slice spiral CT scanner. The images were transmitted to the PACE system and were processed by multi planar reconstruction (MPR) to obtain coronal, sagittal and oblique coronal images. The differences of CT staging, FIGO staging and postoperative pathological staging were compared. Results CT staging diagnosis of 148 patients with cervical carcinoma showed 27 cases of stageⅠa, 41 cases of stageⅠb, 28 cases of stageⅡa, 18 cases of stageⅡb and 6 cases of stageⅢa. Staging was correct in 120 cases, accounting for 81.08%, in which CT and FIGO staging showing no lesions in7 cases. The rate of missed diagnosis was 4.73% which was detected by postoperative exfoliative cytology. CT diagnosed excessive low staging in 8 cases, accounting for 5.41% and excessive high staging in 20 cases, accounting for 13.51%. For FIGO staging, there was excessive low staging in 31 cases and excessive high staging in 28 cases. The diagnostic accuracy was 60.14%. Conclusion The accurate rate of CT perfusion imaging staging is higher than that of FIGO staging and it can provide more information. It can be used as an error correction test after FIGO staging. CT is of important guiding significance in preoperative staging, the selection of operation scheme and prognosis.
【关键词】宫颈癌;CT灌注成像;FIGO 分期;病理分期
【中图分类号】R711.74
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2017.04.035
前言
宫颈癌在妇科恶性肿瘤中排名第三,在我国发病率仅次于乳腺 癌,宫颈癌术前分期是治疗方案疗效保障的基本前提,国际妇产科联 合会(FIGO)将宫颈癌分为四期,并认为Ⅱa期以下患者适用放疗及根 治性手术治疗,而Ⅱb期或Ⅱ期以上患者则采取放疗[1]。目前术前分期 方式主要包括影像学分期及FIGO分期,但FIGO为单纯临床诊断,主要 通过触诊、阴道镜、子宫镜或X线检查,准确率较低[2],有研究调查 发现,FIGO对Ⅰa期-Ⅱa期、Ⅱb期或更晚期的检出率分别为54.7%、 21%,均处于较低水平[3]。而随着CT诊断技术的不断成熟,其用于宫颈 癌术前诊断具有可能性,尤其是多层螺旋CT有较高的空间分辨率及强 大的图像后处理技术,有利于提高分期准确性,但目前有关CT术前分 期与FIGO分期、病理分期比较的研究较少,本次研究选取我院148例经 病理证实为宫颈癌的患者为研究对象,观察CT灌注成像技术在宫颈癌 术前分期中的应用价值,结果如下。
中国CT和MRI杂志
第15卷, 第 4 期
2017年04月
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