摘要
目的 探讨胸腺神经内分泌肿 瘤(neuroendocrine tumors of the thymus,NETT)的临床及CT表现。方法 回顾分析9例病理确诊NETT患者临床及CT 图像,并结合相关文献复习。结果 男性 8例,女性1例,平均年龄57.4岁,临床无 特异性,病理不典型类癌5例,小细胞癌3 例,大细胞癌1例。CT表现前上纵隔体积 较大实性肿块,平均最大经为8.6cm,7 例见坏死,2例见钙化,均具有侵袭性特 点,7例侵及邻近胸膜,3例侵及血管,增 强呈中度不均匀强化,6例瘤内见细小血 管强化影,8例合并纵隔淋巴结肿大,4 例发生转移。结论 NETT以中老年男性多 见,具有体积大、易坏死、明显侵袭性、 不均匀强化、常见瘤内细小血管强化影、 易淋巴转移等特点,CT有助于提高NETT的 准确诊断率,明确受侵范围,指导手术方 案。
Objective To investigate the clinical and CT features of thymic neuroendocrine tumors. Methods The clinical and CT images of 9 patients with pathologically confirmed NETT were retrospectively analyzed. Results 8 males and 1 female, average age 57.4 years old, no difference on clinical features. Pathology included 5 cases of atypical cancer, 3 cases of small cell carcinoma and 1 cases of large cell carcinoma. CT imaging showed a larger volume of solid mass in the anterior upper mediastinal mass, with the average maximum of 8.6cm, 7 cases with necrosis, and 2 cases with calcification. All lesions were invasive features, 7 cases involving the pleura, and vascular invasion in 3 cases, enhanced scan showed moderate inhomogeneous enhancement, 6 cases of tumor in small vessels strengthen the shadow, 8 cases with mediastinal lymph nodes, 4 cases of metastasis. Conclusion Thymic neuroendocrine tumor often occurred in elderly male patients, it has large volume, easy to necrosis, obvious invasion, uneven enhancement, enhancement of small blood vessels was often seen in the tumors, easy lymph node metastasis and so on, which helps to improve the rate of correct diagnosis of NETT, diagnosis depends on pathological examination
【关键词】胸腺;神经内分泌肿瘤;X线 计算机
【中图分类号】R736.3;R445.3
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2017.04.019
前言
胸腺神经内分泌肿瘤(neuroendocrine tumors of the thymus, NETT)是一种很少见的胸腺恶性肿瘤,组织起源尚不明确[1],临床无特 殊症状,影像学报道较少,以个案报道或小样本回顾性研究为主,误 诊情况较多。本文回顾性分析9例经病理证实的NETT患者的临床、病理 及CT图像,以期提高对该病的认识、CT诊断和鉴别能力。
中国CT和MRI杂志
第15卷, 第 4 期
2017年04月
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