目的 调查研究2型糖尿病患者腰 椎骨密度以及影响因素。方法 以2012- 2014年入住我院的76例2型糖尿病患者以 及76例健康体检人员为研究对象，且以2 型糖尿病患者为观察组，健康体检人员 为对照组，比较两组实验对象在不同年 龄、性别、病程、绝经时间等的骨密度以 及骨质疏松发病率情况。结果 两组受试 人员各年龄段骨密度值以及骨质疏松的 发病率无明显差异(P>0.05)；2型糖尿病 患者腰椎骨密度各病程之间无明显差异 (P>0.05)。2型糖尿病患者的腰椎骨密度 与年龄呈负相关，与体质量指数呈正相 关。将年龄作为控制因子，女性2型糖尿 病患者腰椎骨密度与绝经年限负相关(r=- 0.22,P<0.05),与绝经年龄无相关性。结 论 2型糖尿病患者随着年龄的增长其腰椎 的骨密度下降，骨质疏松发病率增加，但 还是和正常人群相仿。而对于女性患者来 说随着绝经年限的延长，其腰椎的骨密度 下降趋势明显。

Objective To investigate the bone mineral density and the influencing factors in patients with type 2 diabetes mellitus. Methods 76 cases of T2DM patients admitted to our hospital during 2012~2014 and 76 cases of healthy persons were studied. T2DM patients were the observation group, and the healthy physical examination personnel were the control group. The bone mineral density and incidence of osteoporosis were compared between the two groups in different age, sex, course of disease, menopause time and so on. Results Bone mineral density in patients with type 2 diabetes was negatively correlated with age, and was positively correlated with body mass index. The age was taken as the control factor, and the female patients were negatively correlated with the years of menopause. Conclusion The incidence of bone density and osteoporosis in patients with type 2 diabetes was similar to the normal group. For female patients, the bone mineral density of the lumbar spine was decreased with the extension of the years of menopause.