摘要
目的 研究不同程度冠状动脉狭 窄CT影像学特点及临床意义。方法 以我 院2013年1月-2015年1月收治的50例疑 似冠心病患者为研究对象,所有患者均 行多层螺旋CT(MSCT)检查,观察冠状动 脉斑块、钙化、狭窄等影像学表现,同 时以冠状动脉造影为标准,分析CT对不 同程度冠状动脉狭窄诊断敏感度、特异 度、阳性预测值及阴性预测值。结果 冠 状动脉狭窄在MSCT上表现为钙化斑块、 软化斑块或混合斑块等特点。以冠状动 脉造影为金标准,MSCT对轻度冠状动脉 狭窄诊断敏感度、特异度、阳性预测值 及阴性预测值分别为85.3%、98.3%、 87.6%、97.9%;中度狭窄诊断敏感度、 特异度、阳性预测值及阴性预测值分别 为91.7%、99.1%、94.8%、98.7%;重度 狭窄诊断敏感度、特异度、阳性预测值 及阴性预测值分别为95.6%、99.5%、 91.5%、99.8%。结论 MSCT诊断冠状动脉 狭窄敏感度、特异度均较高,且冠状动 脉狭窄程度越高,MSCT诊断敏感度及特 异度越高。
Objective To study the imaging features and clinical significance of CT in different degrees of coronary stenosis. Methods From January 2013 to January 2015, 50 patients with suspected coronary heart disease in our hospital were examined by multislice spiral CT (MSCT). The imaging features of coronary plaque, calcification and stenosis were observed. With the results of coronary angiography as the standard, the sensitivity, specificity, positive and negative predictive values of CT in the diagnosis of different degrees of coronary stenosis were analyzed. Results MSCT of coronary stenosis showed calcified plaque, soft plaque and mixed plaque. With the results of coronary angiography as the golden standard, the sensitivity, specificity, positive and negative predictive values of MSCT in the diagnosis of mild coronary stenosis were 85.3%, 98.3%, 87.6% and 97.9%, in moderate stenosis were 91.7%, 99.1%, 94.8% and 98.7% and in diagnosis of severe stenosis were 95.6%, 99.5%, 91.5% and 99.8%. Conclusion The sensitivity and specificity of MSCT are high in the diagnosis of coronary stenosis, and the severer coronary stenosis is, the higher diagnostic sensitivity and specificity are.
【关键词】冠状动脉狭窄;多层螺旋 CT;影像学特点;诊断价值
【中图分类号】R445.3;R543.3
【文献标识码】A
【DOI】10.3969/j.issn.1672- 5131.2017.03.018
前言
冠心病指的是冠状动脉病变使其血液供应与心肌需求失衡造成心 肌损伤,其发病率、病死率呈现逐年增长特点[1]。临床表明冠心病发 病与冠状动脉粥样硬化有关,尤其是冠状动脉狭窄,且冠状动脉狭窄 与其斑块存在一定的联系[2]。目前临床诊断冠状动脉狭窄通常以冠状 动脉造影为依据,但它属于有创操作,成分高,且可能引发相关并发 症,为此临床使用受限。而多层螺旋CT(MSCT)检查具有无创、成分相 对低、后处理技术强大等特点,逐渐成为冠状动脉病变诊断的重要手 段。我院于2013年1月~2015年1月对50例疑似冠心病患者行MSCT检 查,探讨不同程度冠状动脉狭窄CT表现及诊断价值,报告如下。
中国CT和MRI杂志
第15卷, 第 3 期
2017年03月
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