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双源CT与DSA在急诊肺栓塞患者诊断中应用研究*

作者:王显东 吴 军

所属单位:重庆市第三军医大学第二附属医院健康管理科(重庆 400039)

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摘要

目的 研究双源CT与肺动脉造影 (DSA)在急诊肺栓塞(APE)患者诊断中的 应用价值。方法 选取2013年5月至2014 年12月我院收治的APE患者50例入研究 组,另50例非动脉栓塞患者为对照组, 均行双源CT双能量肺动脉成像(CTPA)与 DSA,对比其血管测量参数值、肺动脉 压力及右心室/左心室最大横径比(RVd/ LVd)、最大面积比(RVa/LVa),比较双源 CT、DSA诊断APE的灵敏度、特异度、 准确度,评价影像特征。结果 研究组 肺动脉压力(49.92±1.68)mmHg、RVd/ LVd(1.24±0.31)及RVa/LVa(1.20±0.39) 高于对照组(P<0.05);两组升主动脉直 径比较无显著差异(P>0.05),研究组主 肺动脉直径(31.04±1.58)mm、左肺动 脉直径(22.57±1.84)mm、右肺动脉直 径(25.29±1.64)mm及右下肺动脉直径 (14.29±1.07)mm高于对照组(P<0.05); 双源CT诊断APE的灵敏度86.67%、特异 度100.00%、准确度88.00%与DSA比较 无显著差异(P>0.05)。结论 双源CT与 DSA在APE中具有较高应用价值,其中双 源CT的CTPA可较好显示肺部解剖信息, 而DSA可预测肺动脉高压及肺功能,为 APE的诊断提供依据。

Objective To study the application value of dual-source CT and digital subtraction angiography (DSA) in the diagnosis of acute pulmonary embolism (APE). Methods From May 2013 and December 2014, 50 patients with APE (study group) and 50 patients without APE (control group) in our hospital were enrolled in the study. All subjects underwent dual-source CT pulmonary angiography (CTPA) and DSA. The vascular parameters, pulmonary artery pressure, the maximum right ventricular/left ventricular transverse diameter ratio (RVd/LVd) and maximum area ratio (RVa/LVa) were compared between the two groups. The sensitivity, specificity and accuracy of dualsource CT and DSA in the diagnosis of APE were analyzed, and the imaging findings were evaluated. Results The pulmonary artery pressure [(49.92±1.68) mmHg], RVd/LVd (1.24±0.31) and RVa/LVa (1.20±0.39) of the study group were higher than those of the control group (P<0.05). There was no significant difference in the diameter of ascending aorta between the two groups (P>0.05). The diameters of main pulmonary artery [(31.04±1.58) mm], left pulmonary artery [(22.57±1.84) mm], right pulmonary artery [(25.29±1.64) mm] and right lower pulmonary artery [(14.29±1.07) mm] of the study group were higher than those of the control group (P<0.05). There were no significant differences in the sensitivity, specificity and accuracy between dual-source CT (86.67%, 100.00%, 88.00%) and DSA (91.11%, 100.00%, 92.00%) in the diagnosis of APE (P>0.05). Conclusion Both of dual-source CT and DSA have high application value in the diagnosis of APE. CTPA of dual-source CT can well show the anatomical information of lungs, while DSA can predict high pulmonary arterial pressure and pulmonary function, providing effective basis for the diagnosis of APE.

【关键词】双源CT;DSA;急诊肺栓塞

【中图分类号】R445.3;R563.5

【文献标识码】A

【DOI】10.3969/j.issn.1672- 5131.2017.03.016

前言

肺栓塞为各栓子阻塞动脉系统的疾病或临床综合征,患者肺循环 与呼吸功能均发生障碍,致残率及病死率高,若不及时诊断和治疗可 引起死亡[1-2]。目前肺动脉栓塞的诊断检查包括CT肺动脉成像、DSA、 胸部平片、MRI等,其中DSA被认为是诊断上肢血管性病变的金标准, 可反映血管形态改变动态信息,对细小血管分辨率较高,但其费用较 高,检查的有创性使远端血管栓塞等并发症发生率达2%,双源CT凝聚 了普通CT机精髓,在显示肺组织通气及灌注状态同时,获得全肺解剖 与功能双重信息,目前在国内外已开展研究[3-5]。本文选取2013年5月 至2014年12月我院收治的急性肺动脉栓塞患者50例为研究对象,分析 双源CT与DSA在其诊断中的应用价值,现报告如下。