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论著-头颈部

CT、彩超联合诊断甲状腺癌的价值研究

作者:仇美琴

所属单位:江苏省苏州市吴江区第一人民医院(江苏 苏州 215200)

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摘要

目的 研究断层扫描(CT)与彩色 多普勒超声联合诊断甲状腺癌的应用价 值。方法 回顾性分析收集我院自2014年1 月至2015年9月收治的98例疑似甲状腺癌 患者作为研究对象,本组患者均行CT薄 层扫描及颈部彩超检查,以病理诊断结 果为金标准,对比联合CT、彩超与单一诊 断方法的诊断价值。结果 98例疑似甲状 腺癌患者确诊为TC的患者有82例;CT对乳 头状甲状腺癌诊断的准确率显著高于彩超 (χ2 =3.521,P<0.05)。CT对甲状腺癌诊 断的灵敏度,特异性,阳性预测值和阴 性预测值分别为89.2%,27.3%,70.7%和 56.25%;彩超对甲状腺癌诊断的灵敏度, 特异性,阳性预测值和阴性预测值分别为 88.3%,21.2%,54.8%和62.5%;CT联合彩 超对甲状腺癌诊断的灵敏度,特异性, 阳性预测值和阴性预测值分别为96.2%, 68.4%,92.7%和81.25%。结论 对甲状腺 癌患者联合计算机断层扫描(CT)与彩色多 普勒超声(彩超)进行诊断较单一方法更可 靠,具有较好的临床应用价值。

Objective To study the clinical application value of computed tomography (CT) and color doppler ultrasound on the diagnosis of thyroid carcinoma. Methods A retrospective analysis of 98 cases of suspected thyroid cancer patients from September 2015 to January 2014 were collected as the research object, the patients were treated with CT thin layer scanning and color Doppler ultrasound examination, the diagnosis value of combined CT and color Doppler ultrasound and single diagnostic method were evaluated. Results 82 cases of patients were diagnosed as TC. The accurate rate of CT in the diagnosis of papillary thyroid carcinoma was significantly higher than that of color Doppler ultrasound (χ2 =3.521, P<0.05). The sensitivity, specificity, sensitivity, specificity, positive predictive value and negative predictive value of CT on the diagnosis of TC were 89.2%, 27.3%, 70.7% and 56.25%, respectively. The sensitivity, specificity, sensitivity, specificity, positive predictive value and negative predictive value of color Doppler ultrasound on the diagnosis of TC were 88.3%, 21.2%, 54.8% and 62.5%, respectively. The sensitivity, specificity, sensitivity, specificity, positive predictive value and negative predictive value of combined CT and color Doppler ultrasound on the diagnosis of TC were 96.2%, 68.4%, 92.7% and 81.25%, respectively. Conclusion The combined CT and color Doppler ultrasound on the diagnosis of TC was more reliable on the diagnosis of thyroid cancer than that of CT or color Doppler ultrasound, alone. And it has better clinical application value.

【关键词】计算机断层扫描;彩色多普勒 超声;甲状腺癌;诊断价值

【中图分类号】R322.5+1

【文献标识码】A

【DOI】10.3969/j.issn.1672- 5131.2017.03.015

前言

甲状腺癌(thyroid carcinoma,TC)是临床最常见的头颈部恶性肿 瘤之一,流行病调查表明该病在女性人群发病率显著高于男性,男女 比例约在1:3,5-6.5%的甲状腺结节患者最后被确诊为甲状腺癌[1-2]。 此外,其发病率在近年来的呈逐渐上升的趋势,而临床对该病的最为 有效的治疗方式为外科治疗,术前的准确诊断对于手术方案的制定及 相关预案的设置均有重要的指导意义[3]。但由于该病发生早期的临床 表现较为隐匿,给其早期确诊带来一定困难,往往延误治疗,因此如 何能够及早准确诊断是影响其预后的重要因素。目前临床对甲状腺癌 的主要诊断方法包括高频超声,CT,MRI,超声引导下的穿刺活检以 及核素扫描等,其中以高频彩超和CT凭借其无创,易被接受而在临床 应用最为广泛[4]。随着近年来CT和高频彩超诊断技术的不断成熟及其 临床应用经验的积累,大大提高了临床对甲状腺肿瘤的诊断水平。计 算机断层扫描(CT)与彩色多普勒超声是目前诊断甲状腺癌最主要且最 常用的影像学技术,本文旨在通过分析CT、彩色多普勒超声及二者联 合对甲状腺癌的诊断结果,比较三种诊断方案对甲状腺癌的临床价 值,为临床选择更好的诊断方案提供依据。