目的 采用3D延迟增强MR成像 (dGEMRIC)来检测软骨内成分变化，同时 探讨dGEMRIC评估髋关节发育不良中退 变软骨的价值。方法 选取本院2012年8 月-2014年12月期间经X线片证实为髋关节 发育不良者40例为研究对象，共70个髋关 节。通过采用问卷调查其疼痛情况，并进 行常规MR序列扫描及3D-dGEMRIC检查。 于X线片上测量其外侧中心-边缘角，然 后再结合X线片及MRI对患者髋关节进行 骨性关节炎(OA)Toniss分级。早期OA组 为：Toniss 1级；正常组：患者无疼痛且 Toniss为0级。本次研究采用MR扫描仪来 完成髋关节3D-dGEMRIC数据采集，并进行 放射状重组，选取患者髋关节6个位置来 测量其软骨dGEMRIC指数。结果 Toniss 0级dGEMRIC指数平均为(579.6±25.6) ms，Toniss 1级平均为(500.2±18.9) ms，Toniss2级平均为(438.9±17.6) ms；Toniss 2级明显低于Toniss 1级，P ＜0.05；而Toniss1级明显低于Toniss 0 级，P＜0.05。早期OA组中，其前部和前 上部及上前部、上部软骨dGEMRIC指数明 显低于正常组，P＜0.05；正常组中，患 者关节上前部dGEMRIC指数明显低于上部 区域，P＜0.05；早期OA组中，除前上部 外，上前部dGEMRIC指数明显低于其他区 域，P＜0.05。结论 检测dGEMRIC可有利 于临床诊断髋关节发育中退变软骨病变及 分期。

Objective 3D imaging using delayed enhancement MRI (dGEMRIC) to detect changes in the composition of cartilage, also discussed dGEMRIC assessment of hip dysplasia in the value of the degeneration of cartilage. Methods Select the hospital in August 2012-December 2014 period confirmed by X-ray hip dysplasia in 40 patients, as this study, a total of 70 hip. Their pain by using questionnaires and to conduct routine MR sequences and 3D-dGEMRIC scanning checks. Measured on the outside of the central X-ray - edge angle, and then combined with X-ray and MRI performed on patients with hip osteoarthritis (OA) Toniss classification. Early OA group: Toniss 1; normal group: patients with no pain and Toniss is 0. This study using MR scanner to complete hip 3D-dGEMRIC data acquisition and restructuring radial selected patients hip 6 position to measure its cartilage dGEMRIC index. Results The study found that, Toniss 0 level dGEMRIC index average (579.6±25.6)ms, Toniss an average (500.2±18.9)ms, Toniss2 grade average (438.9±17.6)ms; Toniss 2 level was significantly lower than Toniss 1, P＜0.05; and Toniss1 level significantly lower than Toniss 0 grade, P＜0.05. Early OA group, its front and the front upper and front portion of the upper cartilage dGEMRIC index was significantly lower than the control group, P＜0.05; normal group, patients with joint front portion of dGEMRIC index was significantly lower than the upper region, P ＜0.05 ; early OA group, in addition to the upper front, the front portion of dGEMRIC index was significantly lower than in other regions, P＜0.05. Conclusion DGEMRIC detection may facilitate the clinical diagnosis of hip dysplasia and degenerative cartilage lesions installments.