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论著-头颈部

儿童视网膜母细胞瘤的临床特点与CT表现分析

作者:张 彤

所属单位:陕西省汉中市3201医院眼科(陕西 汉中 723000)

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摘要

目的探讨儿童视网膜母细胞瘤 的临床特点及CT表现。方法 回顾性分析 2010年7月-2015年7月于我院经手术及 病理证实为视网膜母细胞瘤的35例(36 只眼)患儿的临床资料及CT检查结果, 总结儿童视网膜母细胞瘤的临床特点及 CT特征。结果 本组Ⅰ期25例(26眼), 占72.22%(26/36),Ⅱ期10例(10眼), 占27.78%(10/36),Ⅲ期1例(1眼),占 2.78%(1/36);以肿块内钙化为视网膜母 细胞瘤的典型CT征象。结论 儿童视网膜 母细胞瘤以眼球内肿块并钙化为特点, CT诊断对视网膜母细胞瘤钙化敏感度 高,是其临床诊断的首选方式。

Objective To investigate the clinical characteristics and CT findings of retinoblastomas in children. Methods The clinical data and CT findings of 35 children (36 eyes) with retinoblastomas confirmed by operation and pathology in our hospital from July 2010 to July 2015 were retrospectively analyzed and summarized. Results In the study, 25 patients (26 eyes) in phaseⅠaccounted for 72.22% (26/36), 10 cases (10 eyes) in phaseⅡfor 27.78% (10/36) and a case in phase Ⅲ for 2.78% (1/36). Calcification within masses was the typical CT sign of retinoblastomas. Conclusion Masses and calcification within eyeballs are the characteristics of retinoblastomas in children. The sensitivity of CT diagnosis to retinoblastomas is high, which is the first choice for the clinical diagnosis of retinoblastomas.

【关键词】视网膜母细胞瘤;CT特征;诊断

【中图分类号】R739.7

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.03.003

前言

视网膜母细胞瘤是儿童常见眼部肿瘤,起源于视网膜胚胎性核层 细胞,以斜视、白瞳症多见,恶性程度较高,易转移至全身,预后 差,早期诊断困难[1],临床常见非典型视网膜母细胞瘤的误诊报道, 早期确诊及治疗是改善视网膜母细胞瘤患儿预后及保存其视力的关键 [2]。基于此,为总结儿童母细胞瘤的临床特点及CT诊断价值,我院对 收治的35例患儿的临床资料展开了回顾性分析,现报道如下。