摘要
目的研究MRI与CT诊断不同病理 分期前列腺癌患者的准确率。方法 选取 我院61例经确诊的前列腺癌患者为研究对 象,均接受CT平扫/增强扫描(双期动态扫 描)以及MRI扫描,比较两种检测方式对 A/B、C/D期前列腺癌的检测准确性。结 果 本次研究中61例患者A期3例、B期16 例、C期18例、D期24例。CT平扫/增强扫 描对A/B检出率为47.37%,漏诊、误诊10 例,6例误诊为前列腺增生,另4例漏诊, MRI对A/B检出率为89.47%,漏诊2例均为 漏诊,两者比较MRI检出率显著高于CT(P <0.05),CT平扫/增强扫描对C/D检出率 为92.86%,误诊3例包括2例前列腺增生, 1例膀胱癌; MRI对C/D检出率为95.24%, 误诊2例均诊断为前列腺增生,两者检出 率比较MRI稍高,但差异无统计学意义(P >0.05)。结论 MRI诊断A、B期前列腺癌 的准确性较CT平扫及增强扫描明显较高, 主要因A、B期前列腺癌仅前列腺体积增 大,密度无明显变化,且边缘较模糊对CT 诊断产生影响,两种检测方式均可准确检 出C、D期前列腺癌,考虑与癌组织已穿 破被膜,前列腺的形态变化明显有关, 但MRI可对被膜是否被癌细胞侵袭进行判 断,因此较CT诊断价值更高。
Objective To study the accurate rates of MRI and CT in the diagnosis of patients with prostate cancer of different pathological staging. Methods 61 patients with confirmed prostate cancer in our hospital were selected as the research objects. All of them underwent CT plain scan/enhanced scan (dual phase dynamic scan) and MRI scan. The accurate rates of the two detection methods for the detection of A/B and C/D stage of prostate cancer were compared. Results Among 61 patients in this study, 3 cases were of A stage, B stage 16 cases, C stage 18 cases and D stage 24 cases. The detection rate of CT plain scan/enhanced scan for A/B was 47.37%. There were 10 cases missed diagnosis or misdiagnosed, 6 cases misdiagnosed as benign prostatic hyperplasia and 4 cases missed diagnosis. The detection rate of MRI for A/B was 89.47% and 2 cases were missed diagnosed. The detection rate of MRI was significantly higher than that of CT (P < 0.05). The detection rate of CT plain scan/enhanced scan for C/D was 92.86%. 3 cases were misdiagnosed, including 2 cases of benign prostatic hyperplasia and 1 case of bladder cancer; The detection rate of MRI for C/D was 95.24% and 2 cases misdiagnosed were benign prostatic hyperplasia. The detectiin rate of MRI was slightly higher than that of CT (P>0.05). Conclusion The accuracy of MRI in diagnosis of A and B stage of prostate cancer is significantly higher than that of CT plain scan and enhanced scan. The main causes are that only the volume of prostate in stages A and B of prostate cancer increases, there is no significant change of density and the obscure boundaries have impact in CT diagnosis. The two detection methods can accurately detect C and D stage prostate cancer. Considering cancer tissues having worn out the envelopes, the morphological changes of the prostate was significantly related. However, MRI can judge whether the envelopes are invaded by cancer cells or not, so compared with CT, its diagnostic value is higher.
【关键词】MRI;CT;前列腺癌;病理分期
【中图分类号】R737.25
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.03.025
前言
前列腺癌近年发病率明显上升,已成为男性恶性肿瘤第6位的疾 病,以老年患者为主要发病群体,主要是前列腺腺泡细胞异常生长所 致[1]。此病的临床诊断方式众多,包括彩超、CT、MRI等,尽管众多研 究已证实前列腺癌具有特异性病理表现,但病理诊断难度大,主要需 借助手术才可完成[2],而其临床分期的判断对治疗方式的选择以及预 后判断有重要的指导价值[3]。本次研究采取CT平扫及双期增强扫描、 MRI常规扫描对我院61例患者进行诊断,以分析MRI与CT对前列腺癌不 同分期的诊断准确率,现将结果报告如下。
中国CT和MRI杂志
第14卷, 第 3 期
2016年03月
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