目的 探讨脑CTP联合头颈CTA诊 断急性缺血性脑卒中侧支循环的方法及应 用价值。方法 收集拟诊急性脑梗死患者 50例，患者完成CTA、CTP检查后及时行相 关临床治疗。30天后复查头颅CT或MRI平 扫。尝试以“CBV－TTP不匹配，且delay TTP＞6s”方法来判断半暗带，以CBV不变 或轻度升高，TTP明显延迟及CTA判断侧 支循环。结果 TP-CBV诊断半暗带敏感度 95%，特异性69%；CTP诊断侧支循环与CTA 比较，差异无统计学意义(P＞0.05)，敏 感度76%，特异性81%。结论 CBV-TTP不匹 配，且delay TTP＞6s”方法诊断半暗带 准确性较高，CTP诊断侧支循环准确性较 高。脑CTP联合头颈CTA对急性缺血性脑卒 中侧支循环的诊断有较高的应用价值。

Objective To evaluate the methods and value in diagnosing collateral circulation of Acute ischemic stroke with CT perfusion and CT angiography. Methods A total of 50 patients suspected with acute cerebral infarction were collected, After underwent CTA and CTP, timely clinical treatment were took. The head CT or MRI scan was took 30 days after onset. Attempt to defind the penumbra with "CBV-TTP mismatch, and delay TTP＞6s", compared with review ; and determine the collateral circulation with CBV unchanged or slightly elevated, TTP significantly delayed, compare with CTA, evaluated the diagnostic value of CTP. Results As CTP diagnosing penumbra , compared with the results of the review, the difference was not statistically significant (P＞0.05), with a sensitivity of 95% and a specificity of 69%; As CTP diagnosing the collateral circulation , compared with CTA, the difference was not statistically significant (P＞0.05), sensitivity 76% , specificity of 81%. Conclusion Higher accuracy was found with method "CBVTTP does not match, and delay TTP＞6s" to diagnose penumbra, as well as CTP to assess collateral circulation . CTP combined CTA for acute stroke has a high value