论著-头颈部
DWI、T2WI及MR动态增强扫描成像对不同分化小肝癌定量研究
作者:沈继明1 张学琴1 梁宏伟1 陆 健1 王霄英2
所属单位:1.江苏省南通市第三人民医院影像 科(江苏 南通 226006) 2.北京大学第一医院医学影像科 (北京 100034)
PDF摘要
目的定量评估DWI、T2WI及MR 动态增强扫描对不同分化小肝癌SHCC的 影像学诊断价值。方法 30名乙肝肝硬化 患者共30个经病理证实的SHCC病灶,均 行DWI、T2WI及动态增强扫描。分析病灶 在6个序列上的信号特征及强化特征。结 果 ①DWI、T2WI对乙肝肝硬化背景SHCC 的显示率差异无统计学意义(P>0.05)。 ② SNR:DWI>T2WI,各组间SNR差异均有 统计学意义(P<0.05);③动态增强强化 信号特征及包膜显示完整。结论 DWI检 测乙肝肝硬化背景SHCC的SNR最高,优于 T2WI,动态扫描更能显示病灶包膜、反映 SHCC的血供特点。
Objective To assess T2-weighted imaging (T2WI), Diffusion-weighted imaging (DWI), Gradient recalled echo-In phase (IP) and Opposed phase (OP) for quantitative detection of small hepatocellular carcinomas (SHCC) in patients with hepatitis B induced cirrhosis. Methods A total of 30 hepatitis B induced cirrhotic patients with 30 SHCC which were pathologically confirmed, all underwent T2WI, DWI, IP and OP. Analyzed the manifestation of SHCC on the four sequences, measured the signal intensity (SI) of SHCC and liver parenchyma on the four sequences and the standard deviation of noise (SDnoise), compared the detection rate, SNR and CNR of SHCC on T2WI, DWI, IP and OP. Results ① There were no statistically significant difference (P>0.05) among the detection rates of T2WI, DWI, IP and OP. ② SNR: DWI>T2WI, statistically significant difference (P<0.05) could be detected; ③ The envelope and the blood supply characteristics displayed better on IP and OP. Conclusion The SNR for the detection of SHCC on DWI was the highest, which was superior to T2WI, IP and OP, the envelope and the blood supply characteristics displayed better on IP and OP.
【关键词】肝细胞肝癌;肝硬化;磁共振成像
【中图分类号】R445.2;R735.7
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.02.024
前言
肝硬化基础上发生肝癌的风险较高[1],因此早期发现、早期治疗 是提高肝癌患者生存率的关键。笔者通过回顾性研究30个乙肝肝硬化 背景下SHCC T2WI、DWI及MR动态增强扫描表现特点,对小肝癌患者的 影像特点进行总结,从而显著提高病灶定性诊断正确率,现报道如 下。
中国CT和MRI杂志
第14卷, 第 2 期
2016年02月
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