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MRI增强扫描在评估颅脑胶质瘤手术患者预后的临床价值

作者:王 涛

所属单位:四川省广元市第一人民医院放射科 (四川 广元 628017)

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摘要

目的 探讨MRI增强扫描对颅脑胶 质瘤手术患者预后的评估价值。方法 以 我院2014年1月-2015年4月收治的30例颅 脑胶质瘤患者为研究对象,均经手术病理 证实,术前、术后定期行MRI增强扫描, 观察术后MRI表现。结果 术后3d内MRI复 查提示反应性强化4例,多表现为均匀环 状或片状强化;肿瘤残余6例,多为不规 则形态,肿瘤边缘结节或团状强化。肿瘤 复发9例(其中术后3个月复发1例,6-18个 月复发8例),MRI显示术区或术区周围出 现新病灶,增强扫描不规则花环状或结节 样强化。术后1~3个月复查误诊6例(将反 应性强化误诊为肿瘤残余5例、肿瘤复发1 例)。结论 术后3d内行MRI增强扫描对肿 瘤术后切除程度(肿瘤残余)准确显示,对 后续治疗方案制定、预后评估具有十分重 要意义。

Objective To explore the evaluation value of enhanced MRI scan in the prognosis of patients having intracranial glioma surgery. Methods 30 cases of patients with intracranial gliomas treated in our hospital from January 2014 to April 2015 were taken as the research objects. All of the patients were confirmed by surgery and pathology. Enhanced MRI scan was performed regularly before and after operation. The MRI findings were observed. Results In postoperative 3d, MRI reexamination indicated reactional enhancement in 4 cases, most of which manifested as homogeneous and ring or sheet enhancement, tumor residual in 6 cases with irregular shape, nodules or mass enhancement on tumor edge. Tumor recurrence occurred in 9 cases (a cases of recurrence in postoperative 3 months, 8 cases in 6 to 18 months). MRI showed new lesions in the operation area or around the operation area. Enhanced scan indicated irregular garlandlike or nodule enhancement. In postoperative 1 to 3 months, postoperative misdiagnosed 6 cases (5 cases of reactional enhancement misdiagnosed as tumor residual and a case of tumor recurrence). Conclusion Enhanced MRI scan performed in postoperative 3d is of very important significance in accurately displaying the resection degree (tumor residual) after tumor surgery, formulating following therapy plan and evaluating the prognosis of the patients.

【关键词】MRI增强扫描;颅脑胶质瘤

【中图分类号】R445.2

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.02.006

前言

据统计,脑胶质瘤在颅内肿瘤中比较常见,占35%~61%,具有 浸润性生长、容易复发等特点[1],临床治疗方法较多,包括手术、放 疗、化疗等,其中以手术为主。但受脑胶质瘤特点、手术范围等影 响,通常难以完全切除,术后易复发,影响患者预后[2]。为此客观评 估手术切除程度、术后修复征象成为当下影像学及神经外科研究的重 点。MRI增强扫描对肿瘤位置、数目、大小、信号强弱及病灶周边情况 可全面反映,在一定程度上可以评估颅脑胶质瘤手术后情况(特别是肿 瘤残留或复发),为术后提供影像学资料。基于此,本研究对我院收治 的30例颅脑胶质瘤手术患者术后不同时期MRI增强扫描影像资料进行回 顾性分析,报告如下。