摘要
目的探讨研究H型高血压患者冠 状动脉病变诊断中冠状动脉CT技术应用的 价值。方法 选取我院收治的符合入选标 准的原发性高血压患者120例,均行冠状 动脉CT、冠脉造影,以及同型半胱氨酸 (Hcy)水平检测。依据Hcy水平将所有患者 分为H型高血压组和单纯高血压组,对比 CT和冠脉造影关于冠状动脉病变检查结 果,并分析CT技术在H型高血压患者冠状 动脉病变诊断中的应用价值。结果 CT检 测技术和冠脉造影检查结果中,冠状动脉 狭窄阳性率和钙化率差异均无统计学意 义(P>0.05);以冠脉造影结果为“金标 准”,CT检测技术在冠状动脉狭窄和钙化 中阳性预测值均为100.00%,且灵敏度、 准确率和阴性预测值均比较高;H型高血 压组患者冠状动脉狭窄阳性率(72.06%) 较单纯高血压组(50.00%)显著升高(P <0.05),且前者钙化率(51.47%)较后者 (28.85%)显著升高(P<0.05)。结论 H型 高血压患者采用CT检测技术对冠状动脉病 变进行诊断和冠脉造影结果相近,且灵敏 度、准确率、阳性和阴性预测值均比较 高,具有较高的推广应用价值。
Objective To discuss and study the application value of CT technique in the diagnosis of coronary artery disease in patients with H type hypertension. Methods 120 cases of patients with with essential hypertension who were eligible for inclusion criteria treated in our hospital were selected and treated with CT and coronary angiography, and detected the homocysteine (Hcy) levels. According to the Hcy levels, all patients were divided into H type hypertension group and simple hypertension group. The results were compared with CT and coronary angiography. The value of CT in the diagnosis of coronary artery lesions in patients with H type hypertension was analyzed. Results In the results of CT test and coronary angiography, there were no significant differences between the positive rates of coronary artery stenosis and calcification rates(P>0.05).The results of coronary angiography were noted as the "gold standard", and the positive predictive values of CT test in coronary artery stenosis and calcification were 100.00%, of which the sensitivities, accuracies and negative predictive values were higher.The the positive rate of coronary artery stenosis in the H type hypertension group (72.06%) was significantly higher than that in the simple hypertension group (50.00%) (P<0.05), and the calcification rate of the former(51.47%) was significantly higher than that of the latter (28.85%) (P<0.05). Conclusion The results of CT detection technique for the diagnosis of coronary artery disease are closed to those of coronary angiography,and the sensitivity, accuracy, positive and negative predictive values are relatively high, which has a high value of popularization and application.
【关键词】H型高血压;冠状动脉病变; CT技术;应用价值
【中图分类号】R544.1
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.02.020
前言
原发性高血压是临床常见疾病,以体循环动脉压升高为基本表 现。该病和遗传因素、饮食、精神应激以及体重等多种因素均存在相 关性,但是其具体发病机制尚不明确。原发性高血压患病率逐年上 升,以老年人群最为明显,我国目前约有1.8亿人患有高血压病[1]。而 高血压是多种心脑血管疾病的重要诱因,严重影响心、脑、肾等重要 脏器的结构和生理功能,导致器质性病变和功能性障碍,严重者甚至 发生衰竭,给患者的生命健康带来极大威胁。据报道[2],原发性高血 压仍是目前心脑血管疾病死亡率居高不下的重要原因。H型高血压在原 发性高血压中所占比例约为75%,且被认为比单纯高血压引发冠状动脉 病变的风险更高。以往研究表明[3],控制H型高血压疾病进展对预防冠 状动脉病变和脑卒中病发、降低病死率具有至关重要的特殊意义。为 了研究H型高血压患者冠状动脉病变诊断中CT技术的应用价值,将我院 收治的120例原发性高血压患者分别进行CT和冠脉造影检查,并对所得 结果进行细致分析,以期为H型高血压患者冠状动脉病变的防治提供可 行方案。
中国CT和MRI杂志
第14卷, 第 2 期
2016年02月
相关文章