目的利用Mimics软件和快速成 型技术辅助s设计寰椎椎弓根钉个体化置 入方案，辅助行寰椎枢椎骨折、脱位后路 复位内固定手术治疗。方法 对成人寰枢 椎标本进行CT扫描收集数据，将生成数据 导入Mimics软件对寰枢椎标本进行三维重 建，并利用该软件相关功能在三维重建图 像上寻找寰枢椎椎弓根螺钉置入最佳轴线 并对相关数据进行测量；以重建三维图像 为模板，以寰椎后弓及枢椎棘突为解剖标 志，利用卡扣技术设计螺钉置入导向器， 将重建椎体模型及3D导向器图像以STL格 式导入3D打印机，制作椎体模型及导向 器。将应用置钉导向器置钉患者病历资料 进行数据分析，与传统椎弓根螺钉手术患 者病历资料数据进行对比分析。结果 成 功建立了与标本相似度极高的寰枢椎三维 重建图像和实物模型，并成功的制作了置 钉导向器，成功对50例患者在置钉导向器 下进行寰枢椎椎弓根置钉，与传统椎弓根 螺钉手术患者相比，研究组置钉可接受率 为100%显著的高于对照组的置钉可接受率 87.5%(P<0.05)。术后患者JOA评分更高 (P<0.05)。结论 利用Mimics软件和快速 成型技术辅助设计寰椎椎弓根钉个体化置 入方案能偶显著的提高置钉的准确性，能 偶提高治疗效果。

Objective Aided design of atlas pedicle screw placement scheme using Mimics software and rapid prototyping technology, assisted reduction and internal fixation operation in the treatment of posterior dislocation of atlas axis fracture line. Methods CT scan was performed to collect data on adult atlantoaxial specimens, will generate the data into Mimics software for three-dimensional reconstruction of atlantoaxial specimens, and atlantoaxial pedicle screw placement for the best axis in the three-dimensional reconstruction and the related data were measured using the software function; to reconstruct 3D image as a template to the posterior arch of atlas and spinous process of anatomic landmark by the snap design guide screw, the vertebral reconstruction model and 3D guide to STL image format into 3D printer, making the vertebral model and guide. The application of pedicle screw guide medical records were analyzed and compared with the traditional pedicle screw surgery with medical records data. Results Successfully established with high similarity of the atlantoaxial specimens of 3D image and physical model, and successfully fabricated screw guide, successfully performed on 50patients with atlantoaxial pedicle screw in screw guiding device, compared with traditional pedicle screw placement operation, the study group accepted rate of 100% significantly higher than the control group in the nailing acceptable rate of 87.5%, (P<0.05). Patients with higher JOA score (P<0.05). Conclusion Aided design of atlas pedicle screw placement scheme can even improve the accuracy of screw placement using Mimics software and rapid prototyping technology, can improve the therapeutic effect.