目的探讨彩超与CT引导下经皮 肺穿刺活检在周围型肺部肿块诊断中的 临床应用价值。方法 将我院呼吸内科收 治的89例周围型肺部肿块患者按照穿刺 活检方法不同分为彩超引导组(n=51)和 CT引导组(n=38)。彩超引导组行彩超引 导下经皮肺穿刺活检，CT引导组行CT引 导下经皮肺穿刺活检，观察比较两组患 者一次性定位成功率、一次性活检成功 率、病理诊断明确率及并发症发生率。 结果 89例患者均活检取材成功。彩超引 导组一次性定位成功率84.31%低于CT引 导组的97.37%，两组比较差异有统计学 意义(χ2 =4.00，P<0.05)；彩超引导组 一次性活检成功率96.08%高于CT引导组 的92.11%，两组比较差异无统计学意义 (χ2 =0.00，P>0.05)；彩超引导组活检组 织病理检查诊断明确率96.08%高于CT引导 组的94.74%，两组比较差异具无统计学意 义(χ2 =0.07，P>0.05)；两组均未出现血 胸、针道转移、呼吸衰竭等严重并发症， 彩超引导组并发症发生率11.76%低于CT引 导组的13.16%，两组比较差异无统计学意 义(χ2 =0.02，P>0.05)。结论 彩超与CT 引导下经皮肺穿刺活检是一种安全、有 效、可行的临床诊断方法，对于超声能显 示的肺部肿块，建议首选超声引导穿刺活 检，而肺内肿块则选择CT引导穿刺活检。

Objective To investigate the clinical application value of color Doppler ultrasound and CT guided percutaneous lung biopsy in diagnosis of peripheral pulmonary masses. Methods 89 patients with peripheral lung masses in our hospital were divided into color ultrasound guidance group (n=51) and CT guided group (n=38). Guided percutaneous lung biopsy guided by color Doppler ultrasound guided percutaneous lung biopsy guided by CT guided percutaneous needle biopsy, two groups of patients were compared with groups of patients with one-time success rate, one-time success rate of one-time biopsy, pathological diagnosis rate and the incidence of complications. Results All the 89 cases were successful. Ultrasound guided group locate a one-time success rate 84.31% lower than in CT guided group of 97.37%. The difference between the two groups has statistical significance (χ2 =4.00, P<0.05); Ultrasound guided group disposable biopsy success rate was 96.08% higher than that of CT guided group of 92.11%, the difference between the two groups no statistical significance (χ2 =0.00, P>0.05); Ultrasound guided group biopsy pathological examination in the diagnosis of clear rate was 96.08% higher than that of CT guided group of 94.74%, the difference between the two groups with statistical significance (χ2 =0.07, P>0.05); Two groups there were no hem thorax, pin tract transfer, respiratory failure and other serious complications, the ultrasound guided group, the complication rate is 11.76% lower than in CT guided group 13.16% of the, the difference between the two groups no statistical significance (χ2 =0.02, P>0.05). Conclusion Color Doppler ultrasound and CT guided percutaneous lung biopsy is a safe, effective and feasible clinical diagnostic method, the ultrasound can display the pulmonary mass, recommended for the first choice of ultrasound guided biopsy, and the lung mass is selected CT guided biopsy.