目的研究多中心对比分析常规 超声和MRI对胎儿畸形的诊断价值。方 法 对产科门诊收集的50例经常规超声 诊断为胎儿畸形的孕妇进行MRI检查，以 出生后随访结果及临床病理结果为标准 对诊断结果进行多中心对比分析，客观 评价MRI与常规超声的临床诊断价值。结 果 50例孕妇中胎儿畸形主要集中在胸部 畸形，约为26.0%；其次为中枢神经系统 畸形22.0%。两种诊断方法的准确率、特 异性经统计学χ2检验，差异有统计学意 义（P＜0.05）；灵敏性无无统计学意义 （P＞0.05）。结论 ①MRI对胎儿畸形的 诊断中，准确率、特异性高。②常规超声 诊断中容易受干扰，但其操作简单、价格 低廉，临床诊断率相对也较高，因此可作 为筛查的主要手段。③笔者建议临床在对 胎儿畸形的诊断中应联合两种方式进行诊 断，以提高确诊率，同时可避免医疗资源 的浪费。

Objective This paper is to investigate the multi-center comparative analysis on diagnosis value of conventional ultrasound and MRI for fetal abnormalities. Methods Fifty pregnant women with fetal abnormalities admitted by the outpatient of obstetrics confirmed by conventional ultrasound diagnosis undergoing MRI examination, to follow-up results and clinical pathologic results after birth were treated as standards to conduct multi-center comparative analysis, and diagnostic value of MRI and conventional ultrasound clinical was objectively evaluated. Results The fetal abnormalities from 50 pregnant women are mainly focused chest deformity, accounting for 26.0% approximately, followed by central nervous system abnormalities at 22.0%. The diagnosis accuracy and specificity after statistics χ2 test satisfied(P＜0.05) , the differences was significant, and there was not obvious difference in the sensitivity (P>0.05). Conclusion (1) MRI delivers high accuracy and specificity in the diagnosis of fetal abnormalities.(2) conventional ultrasound was susceptible to be interfered in the diagnosis, but it is featured with simple operation, low cost and relatively high clinical diagnosis rate, thus can be used as a major means for screening.(3) the authors suggest joint diagnosis of two ways should be applied in clinical diagnosis of fetal abnormalities in order to improve the diagnosis rate, and can the waste of medical resources may be avoided.