目的探讨CT引导下植入125I放射 粒子治疗纵隔淋巴结转移瘤的方法、疗 效、安全性。方法 38例纵隔淋巴结转移 瘤患者，所有病灶均为术后或放化疗后转 移性病灶。按照“均匀植入原则”，每个 转移灶植入放射粒子12～48粒。术后立 即行CT扫描并进行疗效质量分析验证， 定期CT随访，判定分析疗效。结果 术 后2个月、4个月、6个月肿瘤局部控制有 效率（CR+PR）依次是：81.6%、92.1%、 84.2%；并发症有:粒子咳出、移位1例， 气胸6例，咯血及肺内针道出血6例，进食 疼痛1例。结论 CT引导下植入125I放射粒 子治疗纵隔淋巴结转移瘤，方法简单、疗 效可靠、安全性高，值得进一步应用研 究。

Objective To explore the method, efficacy and safety of CT guided 125I radioactive particles implantation in treatment of mediastinal lymph node metastases. Methods 38 patients with Metastatic Tumor of Mediastinal lymph Nodes, All lesions were lesions and metastasis after surgery or after radiotherapy and chemotherapy. According to "uniform implantation principle", each metastatic implantation of radioactive particle of 12 to 48 grains. Postoperatively, CT scan was immediately performed and the quality was validated．The regular CT scan was conducted to determine curative effect. Results The local control efficiency of 2 months, 4 months, 6 months after operation are: 81.6%,92.1%, 84.2%; The complications included: Particles coughed,shift of 1 cases, 6 cases of pneumothorax,6 cases of hemoptysis and the needle tract hemorrhage in lung, eating sorely in 1 case. Conclusion CT-guided 125I Radioactive Particles Implantation in Treating Metastatic Tumor of Mediastinal lymph Nodes hasing simple method, reliable curative effect and high security is worth further application and study.