论著-头颈部
CT与MRI诊断早期股骨头缺血坏死的多中心对比分析
作者:侯新民1 吕仁发2 夏桂芳1
所属单位:1.江西鹰潭184医院放射科 2.江西鹰潭184医院骨科(江西 鹰潭 335000)
PDF摘要
目的研究CT与MRI对早期股骨 头缺血坏死的临床诊断价值。方法 选取 2013年1月-2015年1月骨科门诊及住院部 收集治疗的早期股骨头缺血坏死患者55例 作为研究对象,所有患者均进行CT(对照 组,55例)及MRI(研究组,55例)检查 诊断,采用多中心对比分析研究方式评估 两种检查方式的准确性、敏感性和特异 性。结果 CT对股骨头缺血性坏死患者检 查主要征象为“新月征”。MRI主要征象 为“线样征”,坏死区域呈现出不同程度 的T1WI、T2WI异常信号。两组诊断准确 率、敏感性及特异性统计学分析差异显著 (P<0.05)。结论 MRI对缺血性股骨头 坏死可进行准确的早期诊断,具有较高的 特异性和敏感性。在CT诊断为阴性的早期 病变中应采用MRI检查诊断以明确诊断, 为患者提供科学合理的治疗。
Objective To investigate clinical diagnosis value of CT and MRI on early ischemic necrosis of femoral head. Methods Fifty patients with early ischemic necrosis of femoral head admitted and treated by the outpatient department of orthopaedics and inpatient department of the Hospital from January, 2014 to January, 2015 treatment were selected as research subjects, all patients underwent CT (55 cases in the control group) and MRI (55 cases in the research group) examination and diagnosis, the research approach of multi-center comparative analysis was implemented to assess the accuracy, sensitivity and specificity of two examination methods. Results Major symptom of CT on patients with ischemic necrosis of femoral head was "crescent sign". Major symptom of MRI was the "string sign", the necrosis area showed abnormal signals with different degrees of T1WI and T2WI. The statistical analysis differences in the accuracy, sensitivity and specificity of diagnosis on patients in two groups were significant (P<0.05). Conclusion MRI is capable of early diagnosis on ischemic necrosis of femoral head with higher accuracy, specificity and sensitivity. MRI diagnosis should be adopted for early pathology diagnosed to be negative via CT in order to make clear diagnosis and provide scientific and reasonable treatment for patients.
【关键词】CT检查;MRI检查;早期股骨头缺血坏死
【中图分类号】R681.22;R445.3;R445.2
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2015.06.030
前言
缺血性股骨头坏死又称作特发性股骨头坏死,具有较高的致残 率;该病的发生与多种因素相关,治疗难度大。发病机制主要为骨组 织的完全或不完全缺血,继发骨组织内营养流失,压迫血管网,引起 静脉流出阻塞,影响骨组织血流供应,导致骨细胞与骨髓细胞发生死 亡;后期修复出现一系列障碍,病情严重时可导致骨组织的缺血性坏 死[1]。股骨头坏死后坏死部位的结构明显发生改变,组织出现塌陷, 骨质(解剖形态)随之遭到破坏,患者出现严重的髋关节周围疼痛,功 能发生进行性减退甚至丧失。早期诊断并治疗对股骨头缺血性坏死患 者具有重要意义[2]。CT和MRI在对股骨头坏死检查上具有各自成像特 点,笔者采用多中心研究分析比较两种检查方式的优劣,现报告如 下。
中国CT和MRI杂志
第13卷, 第 6 期
2015年06月
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