目的研究探讨中短期鼻咽癌放 疗随访中磁共振扩散加权成像的应用价 值。方法 选取我院收治中短期鼻咽癌 放疗患者100例作为研究对象，按照其随 访时间的不同将其分为两组。两大组患 者又根据肿瘤的残留或者复发情况各自 在组内分为残留组(5例)和非残留组(37 例)、复发组(7例)和非复发组(51例)，分 别对各组患者行常规磁共振扫描和磁共 振扩散加权成像检查，观察不同组别患 者的影像学表现，并对其各组患者病灶 位置以及鼻翼外肌的表观扩散系数(ADC) 进行测量和比较。结果 测量所有患者 的鼻翼外肌的ADC值，可见其平均值为 (1.63±0.21)×10-3mm2 /s。距离放疗6个 月内的42例患者中，5例肿瘤残留患者ADC 值为(1.11±0.17)×10-3mm2 /s,38例无肿 瘤残留的患者,ADC值为(1.88±0.23)× 10-3mm2 /s。距离放疗6个月以上的58例中,7 例复发患者的ADC值为(0.81±0.08)× 1 0- 3m m2 /s,51例非复发患者的ADC值为 (1.90±0.23)×10-3mm2 /s。肿瘤残留和复 发患者的ADC值均显著低于鼻翼外肌检测 值，而未残留和非复发患者则显著高于鼻 翼外肌以及肿瘤复发患者的ADC值，比较 均有统计学意义(P＜0.05)。结论 磁共振 扩散加权成像能够对鼻咽癌患者放疗后的 病灶变化情况进行有效的显示，提供细胞 水平的定性与定量信息，且检测的灵敏度 较高，有利于对患者放疗后的肿瘤残余、 复发等情况进行预测和诊断，值得临床推 广应用。

Objective To analyse and medium-term nasopharyngeal carcinoma radiotherapy follow-up the application value of magnetic resonance diffusion weighted imaging. Methods Our hospital in 100 cases of nasopharyngeal carcinoma radiotherapy patients as the research object, according to the different follow-up time will be divided into two groups, one group is the follow-up review time within 6 months after the treatment, a total of 42 cases, another group is the follow-up review between 6 months to a year after the treatment, a total of 58 cases. Two groups of patients and according to the tumor residual or recurrence of each within the group are divided into residual group (5 cases) and non residual group (37 cases), recurrent group (7 cases) and non recurrence group (51 cases), respectively in patients with each line of conventional MRI scans and magnetic resonance diffusion weighted imaging, observation of the imaging appearances of different groups of patients, and the groups of patients with lesion location and dilatory muscle of the apparent diffusion coefficient (ADC) is measured and compared. Results All patients were measured the dilatory muscle of ADC values, is the average of (1.63±0.21) ×10-3 mm2 /s. Distance radiotherapy within 6 months of 42 cases, 5 cases of tumor patients with residual ADC values (1.11±0.17)×10-3mm2 /s., 38 cases of patients with tumor residue, ADC values (1.88±0.23)×10-3mm2 /s. Distance radiation more than six months in 58 cases, 7 cases of patients with recurrence of ADC value is (0.81±0.08) ×10-3 mm2 /s., 51 cases of patients with recurrence of ADC value is (1.90±0.23) ×10-3mm2 /s. Residual tumor and recurrence in patients with ADC values were significantly lower than the dilatory muscle readings, without residue and is significantly higher than patients without recurrence dilatory muscle and ADC values in patients with tumor recurrence, more have statistical significance (P<0.05). Conclusion Magnetic resonance diffusion weighted imaging can changes after radiotherapy in patients with nasopharyngeal carcinoma lesions for effective display, provide a cellular level of qualitative and quantitative information, and the sensitivity of detection is higher, is helpful for the patients after radiotherapy of tumor residual prediction and diagnosis, recurrence, and so on and so forth, worthy of clinical popularization and application.