目的应用MR动态增强判断Ⅱ期 宫颈鳞癌复发的价值及意义。方法 分析 Ⅱ期宫颈鳞癌患者48例(包括12例复发宫 颈鳞癌患者，36例无复发宫颈鳞癌患者) 术前的常规MRI、4D-THRIVE动态增强扫 描以及术后常规MRI，在Matlab平台下对 术前动态增强的兴趣区STC及CTC进行非 线性拟合获得血管通透性相关参数Ktrans， Kep及Ve值，评估复发组和非复发组血管 通透性的特点以及MRI在Ⅱ期宫颈鳞癌术 后随访中的价值。结果 Ⅱ期宫颈鳞癌复 发组的Ktrans，Kep及Ve值较非复发组均升高 (P<0.05)。Ktrans的曲线下面积AUC=0.90, 当Ktrans≥0.73min-1时，其诊断Ⅱ期复发 宫颈鳞癌的敏感性为83.3%，特异性为 77.8%；Kep的曲线下面积AUC=0.81，当 Kep≥0.95min-1时，其诊断Ⅱ期复发宫颈鳞 癌的敏感性为83.3%，特异性为61.1%；Ve 的曲线下面积AUC=0.50，不具有诊断价 值。宫颈鳞癌复发具有特定的MRI表现。 结论 术前MRI动态增强扫描对判断Ⅱ期宫 颈鳞癌复发具有较高诊断效能，术后MRI 定期随访有助于尽早发现宫颈鳞癌的复 发。

Objective To judge the value and significance of stage Ⅱ cervical squamous cell carcinoma recurrence Ⅱ by using dynamic contrast-enhanced MR. Methods Patients with stage Ⅱ cervical squamous cell carcinoma 48 cases (including 12 cases of patients with recurrent cervical squamous cell carcinoma,36 cases of patients with no recurrence cervical squamous cell carcinoma) were obtained preoperative MRI, 4D-THRIVE dynamic contrast-enhanced MRI and postoperative. In Matlab platform region of interest STC and CTC were obtained nonlinear fitting microvascular permeability parameters Ktrans, Kep and Ve values, evaluate recurrence group and no recurrence group vascular permeability characteristics. And to value MRI in postoperative follow-up. Results There were differences between the recurrent cervical squamous cell carcinoma group and no recurrence for Ktrans and Kep(p<0.05),but for Ve(p＞0.05). Area under the curve of Ktrans value is 0.90. When Ktrans≥0.73min-1, diagnosis of stage Ⅱ recurrent cervical squamous cell carcinoma in the sensitivity and specificity were 83.3% and 77.8%. Area under the curve of Kep value is 0.81. when Kep≥0.95 min-1, diagnosis of stage Ⅱ recurrent cervical squamous cell carcinoma in the sensitivity and specificity were 83.3% and 61.1%. While area under the curve of Ve is 0.5, which has no diagnostic value. Recurrent squamous cell carcinoma of the cervix with a specific MRI. Conclusion Preoperative dynamic contrastenhancement MRI to determine stage Ⅱ cervical squamous cell carcinoma has a high diagnostic efficacy of recurrence, postoperative MRI regular follow-up will help early detection of recurrent squamous cell carcinoma of the cervix.