论著-头颈部
腹部肾上腺外、脊柱副节瘤CT、MRI表现与病理对照分析
作者:张 军1 张 岳2 吴政光3 林晨琳2 肖树恺1
所属单位:1.深圳市龙岗区人民医院放射科 (广东 深圳 518172) 2.广州中医药大学第二附属医院 (广东省中医院)放射科 (广东 广州 510120) 3.广东省第二人民医院放射科 (广东 广州 510317)
PDF摘要
目的探讨腹部肾上腺外(腹膜 后、膀胱)、脊柱副节瘤的影像学特征, 以及三期动态增强扫描的诊断价值。方 法 回顾分析19例经病理证实的腹部肾上 腺外、脊柱副节瘤CT(n=17)、MRI(n=3)资 料,将CT、MRI表现与病理对照。结果 19 例均单发,其中,腹膜后12例,CT平扫病 灶均呈不均匀稍低密度,增强后均呈中度 /明显强化,其中,4例呈“渐进性延迟 强化”,镜下所见:瘤细胞排列呈小腺泡 状或实性巢状,间质毛细血管丰富;各6 例、2例强化模式呈“快进慢出”、“慢 进慢出”型,镜下所见:瘤细胞形成器官 样结构,间质内见中等/大量血窦影。膀 胱5例,平扫均呈均匀稍低密度/稍长T1等 T2信号,动态增强扫描,增强模式呈“快 进慢出”型,镜下所见:瘤细胞呈小梁/ 巢状排列,间质血窦丰富。脊柱2例,病 灶内均可见点、匍匐条状流空血管影;均 未见淋巴结转移,1例腹膜后病例出现腰 椎体及附件转移。 结论 腹部肾上腺外副 节瘤CT、MRI表现具有一定特征,三期动 态增强扫描可较好反映肿瘤内部构成,具 有较高诊断价值;脊柱副节瘤较少见,诊 断困难,病灶内“点状、匍匐条状流空血 管征”可能具有一定特征。
Objective To explore the CT and MRI features of abdominal extra-adrenal and spinal paraganglioma and the diagnosis value of three phases dynamic enhancement scanning for it. Methods The CT and MRI findings of 19 patients pathologically confirmed abdominal extra-adrenal and spinal paraganglioma were retrospectively studied and compared with pathological features. Results Single tumor was found in all 19 patients. The disease was located in the retroperitoneum in 12 cases. On the CT plain scan, the leision presented as slightly low attenuation, while in three-phase dynamic enhancement scanning, 4 of them showed "progressive delayed enhancement". The histologic examination showed tumor cells are arranged in an alveolar or nesting pattern, with abundant capillaries in interstitial substance. 6 cases showed "slow in and slow out" enhanced mode and 2 cases showed "fast in and slow out" enhanced mode. Histopathologically, tumor cells formed in organoid patterns, surrounded moderate or abundant hematococoel. 5 cases located in urinary bladder. The leision manifested as homogeneous isodensity on the CT palin scan and slightly hypointensity on T1WI and isointensity on T2WI, while in three-phase dynamic enhance scan, they enhanced obviously in the artery phase, and then drop slowly in the portal and delay phase. Histopathologically, tumor cells showed string-like or nesting pattern , surrounded moderate or abundant hematococoel. 2 cases located in the spine, and multiple punctate and serpiginous structures of signal void due to high-velocity flow were noted around and within the tumors on all sequences were seen. None had lymphatic metastasis, while lumbar vertebral body and accessory metastasis occurred in one case. Conclusion There are certain characteristics of abdominal extra-adrenal paraganglioma, on the CT or MRI imaging. CT dynamic enhancement scanning has a preferable diagnosis value, because it can reasonably reflect the inner composition of the tumors. Paragangliomas occurring in spine are extremely rare, and it is very difficult to diagnose, but the multiple punctate and serpiginous structures of signal void around and within the tumors on all sequences may be the characteristic sign of it.
【关键词】副神经节瘤;腹部肾上腺外; 脊柱;体层摄影术,X线计算机; 磁共振成像;病理
【中图分类号】R736;R445.2
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2015.06.016
前言
副节瘤好发于肾上腺髓质,占85~90%,称为嗜铬细胞瘤[1],肾上 腺外少见,仅占15%[2]。肾上腺外副节瘤好发于腹膜后,肿瘤常无内分 泌功能,容易受忽视,但术中却容易因刺激、压迫或麻醉而诱发高血 压危象,甚至休克[3],因此,术前、早期诊断非常重要。膀胱[4]、脊柱 [5]副节瘤罕见,诊断困难。本文回顾分析19例经病理证实的腹膜后、 膀胱、脊柱副节瘤CT、MRI资料,并与病理对照,探讨其影像学特征及 三期动态增强扫描的诊断价值,以提高诊断水平。
中国CT和MRI杂志
第13卷, 第 6 期
2015年06月
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