目的探讨计算机辅助诊断(CAD) 定量分析对原位腺癌(AIS)与非典型腺瘤 样增生(AAH)的鉴别诊断价值。方法 采用 自编软件对125例经CT发现的磨玻璃样结 节进行组织特征分析，比较AIS和AAH在CT 直方图上的差异。结果 AIS组的病灶平 均直径大于AAH组的，但两者差距无统计 学意义(P>0.05)；AAH组的CT值与CT峰值 均明显小于AIS组，差异具有显著性意义 (P<0.001)；且CT峰值<-620,则AAH的可能 性更大。直方图中，若出现双峰或多峰， 可以除外AAH。结论 基于计算机辅助诊断 技术的组织成分分析能很好的鉴别表现为 磨玻璃样结节的AAH与AIS。

Objective To study the clinical application value of computer-aided diagonosis in differentiating atypical adenomatous hyperplasia from adenocarcinoma insitu. Methods 125 cases of ground glass opacity detected by CT were diagonosized by self-designed soft, to compare the difference between AIS and AAH. Results There was no significant difference in lesion size between AIS and AAH (P>0.05). The peak and mean CT value of AAH were obviously lower than that of AIS,with significant difference (P<0.001). If the peak of CT value<-620,it was more likely to be AAH. In the CT histogram, doublepeak or multi-peak can except for the possibility of AAH. Conclusion Tissue components analysis basede on computer-aided diagonosis can perfectly identify AAH and AIS which appear as ground glass nodules.