论著-头颈部
三维动态增强MRA与DSA诊断下肢动脉硬化闭塞症的对比研究
作者:程大文 高 玲 沈广澍 王庭红 冯 克 仇 阳
所属单位:南京中医药大学第三附属医院放射科(江苏 南京 210001)
PDF摘要
目的评价三维动态增强MRA(3D CE-MRA)诊断下肢动脉硬化闭塞症(ASO) 的准确性及应用价值。方法 通过3D CEMRA和DSA两种不同的影像学检查方法对 ASO成像结果进行对比研究。结果 与DSA 相比较,3D CE-MRA评价ASO的符合率为 90.5%;诊断下肢动脉病变的灵敏度为 98.17%,特异度95.05%,准确率96.67%,阳 性预测值95.54%,阴性预测值97.96%。结 论 对比研究结果表明:DSA仍是目前ASO 诊断的“金标准”,但其具有创伤性、风 险较大且费用高,不适宜作为下肢狭窄的 首选诊断方法。3D CE-MRA对全下肢血管 病变显示有独特优势,具有无创、无辐射 的特点,可作为ASO的主要检测手段。
Objective Evaluated 3D dynamic contrast-enhanced magnetic resonance angiography (3D CE-MRA) diagnosis accuracy and application of arteriosclerotic obliterans (ASO) of the lower limbs. Methods Adopted by the 3D CE-MRA and DSA, the two different image diagnosis methods,the image results of ASO were compa-ratively studied. Results Compared with the results of DSA. Lower limb artery stenosis valuation of 3D CE-MR coincide rate was 90.5%. For lower limb artery lesions diagnostic, the sensitivity, specificity, accuracy, positive pre-dictive value, and negtive predictive value of 3D CE-MRA were 98.17%, 95.05%, 96.67%, 95.54%, and 97.96%,respectively. Conclusion The compared results show that: DSA lower limb artery stenosis diagnosis was "gold standard", but it was invasive, risk and cost. Not suitable for a Lower limb artery stenosis diagnostic first choice method. The 3D CE-MRA has unique advantages on exploring vascular lesions in lower limbs. It was also noninvasive, no radiation and simple that will become the main testing methods for ASO.
【关键词】三维动态增强MRA;数字减影 血管造影;下肢;动脉硬化 闭塞症
【中图分类号】R543.5;R445.2
【文献标识码】A
【DOI】 10.3969/j.issn.1672-5131.2015.02.33
前言
随着人口老龄化及人们生活方式的改变,高血压及糖尿病的发生 率逐年上升,由此引起的下肢动脉硬化闭塞性病变(arteriosclerotic obliterans,ASO)越来越多。数字减影血管造影(digital subtraction angiography, DSA)是公认的诊断下肢动脉病变的“金标准”,但由于 其是有创检查且费用昂贵等原因而无法作为常规检查[1]。三维动态增 强MR血管成像(3D dynamic contrast-enhanced magnetic resonance angiography, 3D CE-MRA)克服了传统MRA的不足,图像质量及对血管 分支的显示有明显提高,几乎达到了与DSA同等水平[2]。本研究回顾性 分析我院收治的35例ASO的3D CE-MRA及DSA检查结果,以探讨3D CEMRA诊断下肢动脉硬化闭塞症的应用价值。
中国CT和MRI杂志
第13卷, 第 2 期
2015年02月
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