目的探讨磁共振 I D E A L和 T 2 mapping成像技术在腰椎间盘退变中的应 用价值。方法 前瞻性选择有腰椎间盘退 变症状的患者30例，分别进行腰椎矢状 位T2 IDEAL成像、矢状位T1Flair加权成 像、横轴位椎间盘T2FSE成像及矢状位T2 mapping成像。在矢状位IDEAL水相位图 像上，参考Pfirrmann分级方法，把L2- L3、L3-L4、L4-L5、L5-S1椎间盘进行分 级，然后在正中矢状位T2 mapping图像 上选择感兴趣区(ROI)，测量椎间盘中髓 核(NP)的T2值，进行统计学分析，比较 分析椎间盘退变分级与T2值之间的相关 性。结果 一共测量120个椎间盘T2值，随 着分级的增加，L2-S1椎间盘NP的T2值减 小，Ⅳ级与Ⅴ级间差异无统计学意义(p＞ 0.05)，其余各级间差异具有统计学意义 (p<0.05)。结论 IDEAL和T2 mapping成像 结合起来分析，定性定量的观察椎间盘退 变情况，在椎间盘退变中具有较高的应用 价值。

Objective To evaluate the clinical value of magnetic resonance IDEAL and T2 mapping imaging in lumbar intervertebral disc degeneration. Methods The prospective pilot study chose 30 patients with symptoms of lumbar intervertebral disc degeneration. Sagittal T2 IDEAL imaging, sagittal T1 Flair imaging, axis intervertebral disc T2FSE and sagittal T2mapping imaging were performed. According to Pfirrmann grading method,discs from L2 to S1 were classified on the sagittal water-phase images. As regions of interest(ROI) were evaluated on water-phase images, T2 relaxation times of nucleus pulposus(NP) were measured. The correlativity between Pfirrmann grade and T2 values was analyzed using statistical analysis. Results Totally 120 discs were measured.The T2 value of NP decreased whlie the Pfirrmann grade increased. The significant diffrernces of T2 value of NP were found in all grades (p<0.05)except for the grade Ⅳ and Ⅴ(p＞ 0.05). Conclusion The IDEAL and T2 mapping imaging could be combined to analysis intervertebral disc degeneration by the way of qualitative and quantitative methods.