目的探讨3.0T MRI T2-mapping在膝关节软骨退变中的临床价值。材料和方法 对46例患者(男26例，女20，平均年龄56岁)膝关节行3.0T  MRI常规序列平扫及T2-mapping成像，对膝关节软骨退变按ICRS标准分级，测量膝关节内外侧髁、髌软骨外侧、内侧软骨T2值。结果  轻度OA组、重度OA组膝关节软骨T2值高于正常组，差异有统计学意义(P<0.05)；重度oa组关节软骨t2值高于轻度组，但差异无统计学意义(p>0.05)。结论  膝关节软骨退变随病变的严重程度T2值增加，MR T2-mapping成像对OA的诊疗具有较高的临床价值。

Objective The aim was to explore the clinical value of T2-mapping in the quantification of degenerative cartilage change at the knee. Methods The study group consisted of 46 patients (26 male and 20 female with average age of 56 years) who underwent MR imaging of knee joint. MR imaging was performed at 3.0 T by using a routine protocol with the addition of an axis T2-mapping sequence. The T2 values In four knee cartilage compartments (the medial and lateral femur and patella) was measured respectively. Results All cartilage compartments showed significant (P<0.05) increase in T2 values between OA group and normal group, but no significant (P>0.05) were found between mild OA group and severe OA group. Conclusion Femoral and patella cartilage T2 values increase with the severity of OA, MRI T2-mapping is valuable for diagnosis and monitoring osteoarthritis.