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论著-头颈部

鼻窦低度恶性肌纤维母细胞肉瘤的影像表现*

作者:杨晓燕1 董 帜2 周丽莎2 崔敏毅3 冯仕庭2

所属单位:1.广州中医药大学深圳附属医院放射科(广东 深圳 510080) 2.中山大学附属第一医院放射科(广东 广州 510055) 3.中山大学附属口腔医院放射科(广东 广州 510055)

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摘要

目的总结鼻窦低度恶性肌纤维 母细胞肉瘤(low grade myofibroblastic sarcoma,LGMS)的影像学表现,以期提高 对该病的诊断水平。资料与方法 回顾性 分析经手术后病理证实的5例LGMS的影像 学表现。5例LGMS均行CT平扫,其中1例行 CT增强扫描,其余4例行MR平扫+增强扫 描。结果 5例LGMS,2例累及右侧上颌窦 及筛窦,2例累及双侧筛窦及蝶窦,1例累 及左侧各鼻窦。5例均表现为窦腔内不规 则形软组织肿块,CT平扫均呈等或稍低密 度;MRI检查,T1WI为中等及稍低信号, T2WI为中等及稍高信号,信号不均匀;增 强扫描5例均可见中度-明显强化。5例肿 瘤周围均出现虫蚀样溶骨性骨质破坏。结 论 鼻窦LGMS的影像学表现为鼻窦内软组 织肿块伴溶骨性骨质破坏,增强扫描中 度-明显强化,影像学检查有助于确定肿 瘤的的侵犯范围。

Objective To evaluate the image features of low-grade myofibroblastic sarcoma(LGMS) of paranasal sinus, and improve the diagnostic accuracy. Materials and Methods A retrospective analysis of 5 cases of paranasal sinus LGMS was carried out. Of the 5 patients, all of them underwent common CT, 1 patient underwent contrastenhanced CT and 4 underwent common MRI and contrast-enhanced MRI. Results Of the 5 patients, 2 occurred in the right maxillary sinus and ethmoidal sinus, 2 occurred in the sphenoid sinus and ethmoidal sinus, 1 occurred in all of the left paranasal sinus. CT scan showed hypo-indense and iso-indense soft tissue mass in the paranasal sinus. T1WI showed isointense mass and T2WI showed isointense and hyperintense mass. Contrast images showed moderate-obvious homogeneous enhancement. All of the 5 cases showed bone destruction. Conclusion LGMS of the paranasal sinus can be characterized as a soft tissue mass with bone destruction, but it is difficult to differentiate from other malignant diseases. Image features can help to determine the extent of the lesion.

【关键词】肌纤维母细胞肉瘤;鼻窦;体层摄影术,X线计算机;磁共振成像

【中图分类号】R445.3;R739.6

【文献标识码】A

【DOI】 10.3969/j.issn.1672-5131.2015.01.14

前言

低度恶性肌纤维母细胞肉瘤(low grade myofibroblastic sarcoma, LGMS)是由肌纤维母细胞分化的间叶性肿瘤,2002年才被WHO 正式命名并分类,可发生于全身各器官,最好发于头颈部和四肢,尤 其好发于是口腔和舌[1]。LGMS非常少见,文献报道不多,迄今国内外 文献报道全身的LGMS总数仅50余例。发生于鼻窦腔的LGMS更为罕见, 目前为止,国内外仅有数个个案报道发生于鼻窦的LGMS,但均缺乏系 统的影像学分析。本文回顾性分析了发生于鼻窦的LGMS的临床、病理 及影像学表现,并结合文献,旨在总结鼻窦LGMS的影像学表现,以期 提高对该病的认识能力及诊断水平。