论著-头颈部
新生儿缺血缺氧性脑病CT及MRI诊断比较
作者:徐恒昀1 曹和涛2 徐金标3
所属单位:1.江苏省阜宁县人民医院CT磁共振诊断中心(江苏 阜宁224421) 2.南通大学附属医院影像中心(江苏 南通 226001) 3.江苏省盐城市妇幼保健院放射科(江苏 盐城 224002)
PDF摘要
目的分析比较CT及MRI诊断新 生儿缺血缺氧性脑病(HIE)的价值。方 法 依据临床通用分度和影像学各自分度 标准,回顾性分析60例HIE临床及CT、 MRI资料,临床和影像分度符合率采用卡 方检验,以P<0.05水准为统计学差异具 有显著性。结果 60例均做了CT检查,其 中25例同时行MRI检查。临床分度:轻度 29例(48.3%),中度21例(35%),重度10 例(16.7%);CT分度:正常7(11.7%)例, 轻度24例(40%),中度20例(33.3%), 重度9例(15%),显示颅内出血21例 (35%)。HIE检出率88.3%。以临床分度为 标准,CT诊断吻合率为82.4%,X2 =10, P=0.019<0.05。MRI检查共25例:轻度 12例(48%),中度9例(36%),重度4例 (16%),显示颅内出血6例(24%)。HIE检 出率100%,与临床分度吻合率达93.5%。 复查CT对轻中度HIE显示率分别为6.5%、 45%,MRI分别为25.3%、58.3%。结论 CT 和MRI检查对HIE的早期诊断、分型及预 后评估有重要价值,MRI优于CT;但蛛网 膜下腔出血检出CT优于MRI。
Objective To compare the value of CT and MRI diagnosis of neonatal hypoxic-ischemic encephalopathy (HIE). Methods Based on clinical and radiographic universal indexing standards, a retrospective analysis of 60 cases of HIE clinical and CT, MRI data was analyzed, The clinical and imaging division compliance rate using the chisquare test, with P<0.05 level for statistical learn the difference was significant. Results 60 cases were all underwent CT, while 25 patients underwent MRI. Clinical grading: 29 mild cases (48.3%) , 21 moderate cases (35%), 10 severe cases (16.7%); CT indexing: normal in 7 cases (11.7%), mild in 24 cases (40%), moderate in 20 cases (33.3%), and severe in 9 cases (15%), 21 cases of intracranial hemorrhage (35%). HIE detection rate of 88.3%. According to clinical grading standard, CT diagnostic agreement was 82.4%, X2 =10, P=0.019 <0.05. MRI examination of 25 cases: mild in 12 cases (48%), moderate in 9 cases (36%), severe in 4 cases (16%), intracranial hemorrhage in 6 cases (24%). HIE detection rate of 100%, consistent with the clinical grading by 93.5%. CT scan of mild to moderate HIE display rates were 6.5%, 45%, MRI were 25.3%, 58.3%. Conclusion CT and MRI have significant value in the early diagnosis, classification and prognosis of HIE, MRI is superior to CT; But CT detection of subarachnoid hemorrhage is superior than MRI.
【关键词】新生儿缺血缺氧性脑病;体层摄影;X线计算机;磁共振成像;对比研究
【中图分类号】R445.2;R748
【文献标识码】A
【DOI】 10.3969/j.issn.1672-5131.2015.01.11
前言
新生儿缺血缺氧性脑病(Hypoxic Ischemic Encephalopathy, HIE),指围生期宫内窘迫、产期窒息,导致脑组织中枢神经缺血缺氧 而受损害,是新生儿窒息的重要并发症,临床上出现系列神经系统异 常表现,发病率和死亡率均较高。重者多伴有一定的后遗症,是造成 残疾儿童最常见的原因之一。强调尽早治疗,综合治疗,三项支持治 疗和三项对症处理。控制惊厥,降低颅内压,消除脑干症状对症处 理,必须在生后三天内及早进行,为专家们共识[1]。影像学检查及时 准确诊断,意义重大,为此笔者搜集60例进行临床影像分析比较,旨 在提高HIE诊断准确率。
中国CT和MRI杂志
第13卷, 第 1 期
2015年01月
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