目的探讨弥散张量白质纤维示 踪术研究分析足月新生儿缺氧缺血性脑 损伤的可行性及其应用。方法 比较50例 不同程度足月新生儿缺氧缺血性脑病的 DTI、MRI表现差异，并且分析其FA值以 及临床新生儿行为神经测查方法的相关 性。结果 不同程度缺血缺氧性脑疾病 在不同区域内的FA值比较，差异具有统 计学意义(P＜0.05)，对中度脑损伤和重 度脑损伤组织之间没有统计学意义(P＞ 0.05)。缺氧缺血性脑病越严重，FA值下 降越明显。各个ROI对应的FA值与评分呈 正相关。结论 弥散张量白质纤维示踪术 可以应用在足月新生儿缺氧缺血性脑病 的评估中。

Objective To investigate the application and feasibility of diffusion tensor white matter fiber tracer technique in the full-term newborn hypoxic ischemia injury. Methods Compared the DTI and MRI differences of the 51 cases of full-term newborn hypoxic ischemia, and analyzed the relativity between FA values and the clinical Neonatal Behavior Neurological Assessment (NBNA). Results The FA values of different areas of different areas of different degrees of ischemia anoxic brain disease has statistical significance (P ＜0.05), there is no difference between the moderate brain injury and severe brain injury (P ＞0.05). The more serious of the hypoxic ischemia encephalopathy, the lower FA values it had. Each ROI corresponds to the FA value and scores were positively correlated. Conclusion Diffusion tensor white matter fiber tracer technique can be applied in the assessment of full-term newborn hypoxic ischemia encephalopathy.