Objective To investigate the optimal energy level for monochromatic reconstruction of coronary CT angiography with the use of cardiac spectral imaging. Methods 17 patients (HR<65/min,variation<3/min) underwent cardiac spectral imaging using GSI mode on a 64-slice CT scanner(Discovery CT 750 HD,GE healthcare). In 6 sets of monochromatic images(40,50,60,70,80 and 90kev), region of interest was put in the aortic root,signal-to-noise,contrast-to-noise and image quality(graded on a 5-point scale) were assessed in all monochromatic images and compared with the conventional polychromatic images. Results Compared with conventional polychromatic images and other monochromatic images, reconstruction with 70kev showed the highest SNR(39.39±5.56) and CNR (30.47±4.77). there was statistical difference on images noise (11.57±1.34vs16.63±1.97),subjective image score(4.72±0.56vs4.57±0.58),and percentage of segment of 5 point(85% vs 71%) between 70kev and polychromatic images(P<0.05). Conclustions Cardiac Spectral Imaging with reconstruction of 70kev offers best image quality of coronary CTangiography compared with other monochromatic images and polychromatic images.