Head and Neck Imaging
VBM Study of Brain Structure in Patients with Chronic Pain of Lumbar Disc Herniation*
Author：DONG Shuai-ke, ZHAO Hong-zeng
affiliation：Second Clinical College of Xinxiang Medical College, Xinxiang 453003, Henan Province, China
PDFAbstract
Objective To study the changes of brain structure in patients with chronic lumbar disc herniation (LDH) by using Voxel based morhometry (VBM). Methods 58patients were diagnosed as lumbar disc herniation with a duration of more than 3 months(LDH). 46 healthy volunteers were the normal control group (HC) The 3D magnetic resonance imaging was performed on 104 subjects. The magnetic resonance data were analyzed by spm-VBM software. Finally, REST and AFN software was used for statistical analysis. Results Compared with HC group, the volume of white matter (WM) in LDH patients was significantly different in the right cingulate gyrus, left frontal lobe, left superior temporal gyrus, Left inferior parietal lobule(P＜0.05). In the right anterior lobe of cerebellum, right precentral gyrus, right posterior lobe of cerebellum, left fusiform gyrus, left superior frontal gyrus, right caudate nucleus, right middle frontal gyrus, left middle temporal gyrus, right cingulate areas of gray matter (GM) volume differences(P ＜0.05). Conclusion Can be found in chronic phase LDH patients with pain of brain gray and white matter differences between regions by using the VBM software, can provide effective value for clinical treatment and prognosis.
【Keyword】Lumbar Disc Herniation; Chronic Pain; MRI; VBM; Gray Matter; White Matte
【Chart number】R323.3+3
【Document Identification Number】A
【DOI】10.3969/j.issn.1672- 5131.2018.06.038
Chinese journal of CT and MRI
th16Volume， th 6 Issue
2018Year06Month
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