Objective To analyze the CT imaging characteristics of pulmonary ground glass density nodules and their correlation with pathological features. Methods 86 patients with pulmonary ground glass density nodules examined by CT in the hospital from January 2015 to December 2017 were enrolled in the study, and their CT imaging data, including the location, size, shape, boundary, internal structure and surrounding structure were analyzed retrospectively. Results Lesion of the 86 patients were single lesions. 35 cases were pure pulmonary ground glass nodules and 51 cases were pulmonary ground glass nodules. Lung cancer or precancerous lesions accounted for 65.12%(56/86), and benign lesions accounted for 34.88% (30/86).The proportion of fuzzy boundary in benign lesionswas significantly higher than that inlung cancer or precancerous lesions, while proportions of clear and coarse boundary,lobulation of lesions edge and spiculation were significantly lower than those in lung cancer or precancerous lesions. The proportions of pleural indentation and vascular convergence sign in benign lesions were significantly lower than those in lung cancer or precancerous lesions, while the proportion of interlobular septal thickening was significantly higher than that in lung cancer or precancerous lesions(P<0.05). However, there was no significant difference in CT signs, such as the location, size, shape, smooth boundary, air bronchogram and lacuna containing airbetween benign and malignant lesions (P>0.05). Conclusion There are differences between benign and malignant ground glass nodules in the boundary, edge and surrounding structure of lesions, which can provide references for diagnosis and differential diagnosis of benign and malignant ground glass nodules.