bjective To investigate the clinical value of plain and enhanced CT scan in the diagnosis of right frontal temporal parietal glioma. Methods Retrospectively analyze plain and enhanced CT scan data of 38 right frontal temporal parietal glioma patients from January 2014 to January 2016, and comprehensively analyze CT imaging characteristics of tumor size, type, the relationship with the surrounding tissue and lesion level. Results According to diagnosis, among 38 patients, there are 26 cases of astrocytoma, 7 cases of small sticks glioma, 3 cases of ependymoma and 2 cases of medulloblastoma. There are 6 cases of low-grade gliomas in, 32 cases of high-grade gliomas. 11 patients are diagnosed as right ventricle narrowing due to pressure, 4 cases are associated with bleeding in the brain. Conclusion Plain and enhanced CT scan can effectively diagnose the shape, size, location and stage of glioma and the relationship with surrounding organs, which is of great clinical importance and is worthy of further spread and application .