Objective To investigate and compare contrast-enhanced ultrasound, CT and MRI in the diagnosis of ovarian tumors. Methods Retrospective analysis 63 cases of patients with the clinical pathological diagnosis of ovarian tumors contrast-enhanced ultrasound, CT and MRI image data, and compared with pathology results. Results MRI diagnosis coincidence rate, sensitivity, specificity, slightly higher than the contrastenhanced ultrasound examination, but is no difference between groups (P>0.05). The CT diagnostic accuracy is lower than the MRI, CT (P<0.05). Contrast-enhanced ultrasound, benign tumor or solid composition mainly show is from the surrounding the tumors had to internal perfusion, cystic components mainly visible capsule wall show cricoid uneven thickening. Malignant solid composition is mainly organization have different degrees of enhancement, most of the tumor inside the body to the peripheral lesion enhancement. Cystic components mainly organization within the capsule wall and separated. On CT manifestations, benign tumors with cystic, enhanced scan without obvious strengthening. Malignant tumors have Ye Zheng "points", or multilocular; Give priority to with solid composition is uniform or non-uniform strengthen after enhancement scanning, a cystic component mass no obvious reinforcement after enhanced scanning. MRI performance, benign cystic components is given priority to organize complex signal, cystic wall enhancement scanning interval reinforced with light and heavy. Solid component organization mainly visible MRI signal is irregular, solid part is the uneven delay after enhancement scanning reinforcement. Malignant tumor is given priority to with capsule real STD focal or real STD focal, pouch or solid tumor, solid cystic component for T1WI low signal, high T2WI signal, the capsule wall formed a nodule or papillary outside protruding out of the sac sac. Solid part of T1WI low or mixed signal, high T2WI signal, enhanced scan be excessie significantly improved. Solid tumor signal is uneven, uneven enhancement scan signal, some see ascites had invasion, lymph node metastasis or pelvic cavity. Conclusion contrast-enhanced ultrasonography is the first choice for differential diagnosis of benign and malignant ovarian tumor imaging.