Objective To observe the clinical manifestations of computed tomography (CT) and magnetic resonance imaging (MRI) for schwannoma and to analyze and compared the application value of the two in the diagnosis and treatment of the disease. Methods The clinical data of 24 patients with hilar bile duct schwannomaconfirmed by surgery and pathology who were treated in the department of surgical oncology in our hospital between March 2009 and July 2014 were retrospectively analyzed. The manifestations of MRI and CT of patients with surgical and pathological schwannoma were analyzed and compared, and the application value of the two diagnostic methods was evaluated.Results Twenty-two cases were single lesions, 2 cases had 2 lesions, a total of 26 lesions.Twentyfour were cystic solid lesions, and 2 were solid lesions. CT plain scan showed that there was round, oval or slightly low density mass with clear boundaries and low-density cystic areain hepatic hilar region, its upper region and top of the the pancreas;MRI scan showed that the solid part of the lesions manifested slightly lower or equal signal on T1WI andequal or slightly higher signal on T2WI. Enhanced scan showed inhomogeneous or progressive delayed enhancement, and no enhancement in necrotic cystic area. Both of CT and MRI can clearly show the whole surrounding of the lesions, and the boundaries were clear. The cases showed that the tumorswere with complete capsule, and the tumor cells were spindle shaped. Conclusion Both of CT and MRI is of high application value in diagnosis of schwannoma, and the hilar hepatic duct schwannomas are with characteristic imaging features. CT and MRI can better localize and diagnose, providing scientific theory basis for clinical diagnosis and treatment.