Objective To discuss the imaging manifestations and misdiagnosis reason of askin tumor. Methods 16 cases of askin tumor confirmed by surgically and histopathologically were included in this study. Those MSCT signs and misdiagnosis reasons were summarized. Results 16 cases of askin tumor age from 4.6 to 32.4 years old, median patient age was 19.6 years old, including 10 males and 6 females. All the cases had no evidently history of exposure to asbestos. The imaging manifestations of askin tumor often occurred in the chest-lung junction region, inhomogeneous density, 1 case showed calcification, ill-defined, showed intense but inhomogeneous enhancement following contrast administration, 15 cases had the feature of adjacent structures involvement, 9 cases with little pleural effusion. Preoperative diagnosis was correct in 5 cases, 6 cases were misdiagnosed with thymoma, 4 cases were misdiagnosed with malignant pleural mesothelioma,1 case was misdiagnosed with peripheral lung cancer. Conclusion Askin tumor is easily occurred in young male without evidently history of exposure to asbestos; often show inhomogeneous density in the chest- lung junction region, with infiltration diffuse growth. Pleural effusions is very common, but common in calcification and adjacent lymph node metastasis. Combined with imaging and clinical is the key to reduce misdiagnosis in practical work.