Head and Neck Imaging
To Evaluate the Value of 3.0 MR Diffusion Tensor Imaging in Cerebral Glioma Grading
Author：HAN Wu, MAO Yi-pu, MA Long-mo,et al.
affiliation：Department of Radiology, Guangxi Zhuang Autonomous Region People's Hospital, Nanning 530021, Guangxi Province, China
PDFAbstract
Objective To evaluate the value of diffusion tensor imaging（DTI）in cerebral glioma grading at 3.0T. Methods Thirty-one patients with pathologically confirmed cerebral glioma underwent DTI measurement. The values of FA of tumor tissues were measured and were correlated to the grade of cerebral gliomas by KruskalWallis H test. ROC analysis was used to assess the FA and ADC to distinguish between low-grade glioma (LGG) and high grade glioma (HGG). Results The FA values were (139.4±81.3) and (103.1±41.5) for LGG) and HGG, respectively. The ADC values were (1.36±0.21)×10-3mm2 /s and (1.09±0.28)×10-3mm2 /s for LGG and HGG, respectively. Statistical significance of FA and ADC values were found between LGG and HGG (P<0.05). Area under curve (AUC) of ADC/FA was 0.79/0.62, the sensitivity was 58.8%/94.1% and the specificity was 92.9%/35.7%, with a threshold value of 1.11×10- 3 (mm2 /s)/178.9. Conclusion The DTI parameter-FA and ADC have the potential clinical importance for cerebral glioma grading.
【Keyword】Cerebral Glioma; Diffusion Tensor Imaging; Pathology
【Chart number】R246.5
【Document Identification Number】A
【DOI】10.3969/j.issn.1672- 5131.2017.10.005
Chinese journal of CT and MRI
th15Volume， th 10 Issue
2017Year10Month
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