Objective To study the characters of CT perfusion for patients with hepatitis B cirrhosis accompanied by primary hepatic carcinoma, and to explore the clinical value of the evaluation by 320-row dynamic volume CT perfusion imaging on hepatic function reserve of patients with primary hepatic carcinoma resulting from hepatitis B cirrhosis. Methods The Toshiba "Aqualion One" 320-row dynamic volume CT was taken to conduct CT perfusion scanning on the 35 patients with primary hepatic carcinoma accompanied by different degrees of hepatitis hepatocirrhosis. The patients were divided into three grades, that is, Grade A, Grade B, and Grade C, according to the Child-pugh classification standard (including 14 cases of Grade A, 11 cases of Grade B, and 10 cases of Grade C).Then,comparison was conducted on the three perfusion values obtained by the measurement of the two doctors as well as the perfusion values (HAP, PVP, and HAPI) of the patients graded according to Child-pugh so as to see whether there was of statistical differences, numerical average of two doctors measured were taken,and analysis had been conducted on the spearman correlation between all the perfusion values and Childpugh classification. Results 1.There was no significant statistical differences between the two groups of perfusion values measured by the two doctors from the Department of Radiology (P＞0.05, See Table 3). 2.There was no significant statistical differences among the HAPs of the patients at Grade A, Grade B, and Grade C (P＞0.05), but there were significant statistical differences among the PVPs and HAPIs of the patients at Grade A, Grade B, and Grade C (P＜0.05). Then S-N-K analysis were conducted on PVP, HAPI, and TLP of the patients at Grade A, Grade B, and Grade C, and the results included that there was no statistical difference between Grade B and Grade C (P＞0.05) but there were statistical differences between Grade A and Grade B and between Grade A and Grade C (P＜0.05). 3. There was no significant correlation between the HAP changes and the Child-pugh classification but there was significant correlations among PVP, HAPI, and C-P classifications, among which there was significant negative correlation between PVP and the C-P classification with the correlation coefficients as r=-0.773 (P＜0.001).while there was significant positive correlation between PVP and HAPI with the correlation coefficient as r=0.676 (P＜0.001). Conclusion PVP and HAPI could be act as the important indexes for the evaluation of hepatic function reserve of patients with hepatic carcinoma resulting from hepatitis B cirrhosis, but in this research it has been proved that it was of no great meaning to take HAP to evaluate the hepatic function reserve.