Objective to investigate the evaluation effect on postoperative efficacy of Computed Tomography (CT) after liver cancer TACE surgery and its diagnositic value on the activity of residual lesions, and to provide the reference for clinical practice in the future in order to improve the diagnositic level of postoperative efficacy after liver cancer TACE surgeries. Methods 68 liver cancer patients undergone transcatheter arterial chemoembolization (TACE) were selected as the research object, and they were given the CT examination in 1 to 3 months after surgery, and finally the effect on postoperative efficacy of CT after liver cancer TACE surgery and its diagnositic value on the activity of residual lesions were explored. Results The comparison between examination results of CT and that of DSA was analyzed, the difference was not statistically significant(p>0.05). The differences in diagnostic sensitivity, specificity and accuracy of CTand that of DSA examination were not statistically significant(p>0.05). Conclusions CT has important diagnositic value on the evaluation of postoperative efficacy of liver cancer and the activity of residual lesions. The images are of certain characteristics, the detection sensitivity and preparation rate are considerable on tumor residues after the treatment of TACE, and it is able to provide more information for predicting the treatment efficacy and judging prognosis of survival and to provide the basis of subsequent treatment of patients.