Objective This paper is to investigate the correlation between color Doppler ultrasongraphy applied on carotid artery IMT, plaques and ischemic cerebral apoplexy, and to offer the references for clinical practices in the future. Methods Ninety eight patients with ischemic cerebral apoplexy admitted by the Hospital during the period from May, 2013 toSeptember, 2014were selected as research object, and 84 patients without cardiovascnlar and cerebrovascular diseases were selected into the control group to study, the correlation between carotid artery IMT and plaques and ischemic stroke was explored, and the diagnosis value of color Doppler ultrasongraphy was investigated. Results The incidence rate for IMT thickening and plaque formation of patients in the stroke group was significantly higher than that of patients in the control group (p < 0.05). The hypertension, hyperglycemia, hyperlipidemia, and smoking conditions of patients in the stroke group were significantly higher than that of patients in the control group (p <0.05), and the differences were statistically significant. Conclusions The carotid artery plaque and the stenosis mainly occur in aged populations, and they are closely correlated to the occurrence of ischemic cerebral apoplexy. The color Doppler ultrasongraphy poses noninvasive advantage, and it can clearly shows the position and extent of the plaque in the carotid artery, delivering great significance on the prevention and control over the occurrence of cerebral apoplexy among aged populations.