Head and Neck Imaging
Quantitative Analysis of Dynamic Contrast Enhanced MRI for Assessing the Microvascular Permeability of Cervical Squamous Cell Carcinoma*
Author：朱志军
affiliation：深圳市妇幼保健院放射科 (广东 深圳 518028)
PDFAbstract
Objective To study the cervical squamous cell carcinoma microvascular permeability characteristics and clinical significance by using 4D-THRIVE dynamic contrast-enhanced MRI. Methods The maximal values of Ktrans and Kep and Ve from 72 patients with cervical squamous cell carcinoma (44 with stage II , 28 with stage III ) and 30 with no cervical carcinoma for controlled group were obtained by 4D THRIVE DCEMRI. In Matlab platform interest in the region STC and CTC were obtained nonlinear fitting microvascular permeability parameters Ktrans, Kep and Ve values, assess normal cervix, cervical squamous cell carcinoma II, III characteristics and vascular permeability. Results There were significant differences between the controlled group and patients with cervical squamous cell carcinoma for Ktrans and Kep and Ve (p＜0.05). Significant differences were also obtained between stage II and stage III for Ktrans and Kep(p＜0.05), but for Ve (p＞0.05). Conclusion Our results suggest that microvascular permeability from quantitative analysis of DCE-MRI is helpful for staging cervical squamous cell carcinoma.
【Keyword】 Cervical Squamous Cell Carcinoma; Microvascular Permeability; Clinical Stage
【Chart number】R711.74
【Document Identification Number】A
【DOI】10.3969/j.issn.1672-5131.2015.03.22
Chinese journal of CT and MRI
th13Volume， th 3 Issue
2015Year03Month
Related articles
Editor email：（1）中国CT和MRI杂志：ctmri@vip.163.com；（2）罕少疾病杂志：hs1999@vip.163.com
Contact number：0755-83695203
Our address：
English
简体中文
logged in
Wechat
TouTiao