目的 研究缬沙坦胶囊联合前列地尔注射液对糖尿病肾病的治疗效果。方法 研究年限为2013年12月-2014年12月， 对象为肾内科收入治疗的30例糖尿病肾病患者，基于治疗方式划分成对照组(15例，缬沙坦胶囊治疗)和观察组(15 例，缬沙坦胶囊联合前列地尔注射液治疗)；对照研究两组患者的临床治疗效果及肾功能改善情况。结果 两组患者 治疗后空腹血糖、糖化血糖蛋白、舒张压、收缩压、尿蛋白排泄率、血肌酐值、尿素氮、ACR等指标经统计学t检 验，P均＜0.05，具有显著差异性。结论 缬沙坦胶囊联合前列地尔注射液可有效改善糖尿病肾病患者的肾功能，降 低尿蛋白排泄，稳定血压和血糖，疗效显著，建议在临床中优先选择使用。

Objective To investigate the treatment efficacy of Valsartan Capsules in combination with Alprostadil Injection to the diabetic nephropathy. Methods The research duration extends from December 2013 to December 2014, 30 patients with diabetic nephropathy were selected as research subjects, who were divided into the control group (15 cases,treatment with Valsartan Capsules) and the observation group (15 cases, Valsartan Capsules combination with Alprostadil Fat Emusiom Injection treatment) based on treatment methods. Clinical treatment efficacy effects and renal function improvements in two groups were applied with comparative research. Results The fasting glucose, glycosylated protein, diastolic blood pressure, systolic blood pressure and excretion rate of urinary albumin, serum creatinine, urea nitrogen, and ACR indicators of two groups patients had statistic difference, the P<0.05. Conclusions Valsartan Capsules in combination with Alprostadil Injection can effectively improve renal function, reduce urinary protein excretion, and stable blood pressure and blood sugar in the patients of diabetic nephropathy and it is preferred to be used in clinical service.