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·头颈疾病·

SWI在继发性癫痫病因诊断中的价值(附10例分析)

作者:李俊晨 谈炎欢 李国华 鱼 汀

所属单位:南京中医药大学常熟附属医院 (江苏 苏州 215500)

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摘要

目的 探讨磁共振磁敏感加权成像(SWI)在继发性癫痫病因诊断中的应用价值。方法 收集本院10例临床检查包括 CT阴性但脑电图异常的癫痫患者行常规MRI扫描及SWI检查。结果 10例癫痫患者中4例常规MRI及SWI检查为阴性,6 例SWI检查均为阳性,其中4例为脑静脉性血管畸形,清晰地显示了粗大的引流静脉及扩张的髓静脉,呈明显低信 号,表现典型“海蛇头”样特征;2例为海绵状血管瘤,病灶中心为等、低、高混杂信号,周围呈典型“铁环” 征。结论 磁敏感加权成像对于无因可循的继发性癫痫诊断具有明显优势,比普通MRI序列更敏感地显示脑静脉性血 管畸形及海绵状血管瘤的影像特征。

Objective To explore the clinical value of susceptibility weighted imaging (SWI) in the diagnosis of secondary epilepsy. Methods Ten epilepsy patients were collected and underwent routine MRI and SWI scans,all of them had normal CT scan and abnormal electroencephalogram. Results Four of ten patients’ cranial MRI and SWI scans prompted normal. Six of ten patients’ were abnormal, in which four were cerebral venous malformation, dilated pulp veins and gross draining vein were all clearly shown by SWI, low signal and typical "caput medusae" sign was shown; Two of six were cavernous hemangioma, the lesion center for mixed signals of low and high and typical “iron ring” sign around were shown by SWI. Conclusion Susceptibility weighted imaging has obvious advantages in diagnosis of secondary epilepsy, and more sensitive to show the typical image of cerebral venous malformation and cavernous hemangioma than ordinary MRI sequence.

【关键词】脑疾病;癫痫;磁共振成像;磁敏感加权成像

【中图分类号】R74;R65

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2015.02.010

前言

癫痫是神经系统疾病中较常见的一组征候群,系 多种原因引起脑部神经元群阵发性异常放电所致的发 作性运动、感觉、意识、精神、植物神经功能异常的 一种疾病。癫痫的主要检查方法有脑电图、CT及MRI 等,有部分患者上述检查均呈阴性,这给临床诊治带 来了一定的难度。磁敏感加权成像(SWI)可充分显示 组织间内在的磁敏感特性差别,能显示静脉血、红细 胞不同时期的降解成分、铁离子等的沉积,在中枢神 经系统得到了广泛应用。本研究旨在探讨SWI对于继 发性癫痫病因诊断中诊断出脑静脉性血管畸形的应用价值。