目的 观察磨玻璃结节(GGN)肺腺 癌患者CT征象特点，分析CT征象对GGN肺 腺癌浸润前病变和浸润性病变的鉴别诊断 价值。方法 回顾性分析2017年1月至2018 年1月我院38例GGN肺腺癌患者的临床资 料。比较GGN肺腺癌浸润前病变和浸润性 病变的CT征象特点差异，分析CT征象的鉴 别诊断价值。结果 GGN肺腺癌浸润前与浸 润性病变分叶征、空气支气管征、胸膜凹 陷征差异有统计学意义(P＜0.05)。鉴别 pGGN肺腺癌浸润前与浸润性病变临界值为 10.5mm，病灶直径ROC曲线显示曲线下面 积(AUC)83.3%，诊断灵敏度、特异度分别 为73.4%、86.7%。鉴别mGGN肺腺癌浸润前 与浸润性病变临界值为13.8mm，病灶直径 ROC曲线显示AUC 78.2%，诊断灵敏度、特 异度分别为71.3%、75.8%。结论 GGN肺腺 癌浸润前与浸润性病变CT征象存在一定差 异，病灶直径有助于鉴别不同性质GGN肺 腺癌浸润前与浸润性病变。

Objective To observe the CT signs features in patients with ground-glass nodule (GGN) lung adenocarcinoma, and analyze the value of CT signs in the differential diagnosis of preinvasive lesions and invasive lesions of GGN lung adenocarcinoma. Methods The clinical data of 38 patients with GGN lung adenocarcinoma from January 2017 to January 2018 were retrospectively analyzed. The differences in CT signs features between preinvasive lesions and invasive lesions of GGN lung adenocarcinoma, and the differential diagnosis value of CT signs was analyzed. Results There were significant differences between the preinvasive lesions and invasive lesions of GGN lung adenocarcinoma in the lobulated sign, air bronchogram and pleural indentation (P<0.05). The critical value of pre-invasive lesions and invasive lesions of pGGN lung adenocarcinoma was 10.5 mm, and the ROC curve of lesion diameter showed the area under the curve (AUC) was 83.3%, and the diagnostic sensitivity and specificity were 73.4% and 86.7% respectively. The critical value of preinvasive lesions and invasive lesions of mGGN lung adenocarcinoma was 13.8 mm, and the ROC curve of lesion diameter showed AUC was 78.2%, and the diagnostic sensitivity and specificity were 71.3% and 75.8% respectively. Conclusion There are some differences in CT signs between preinvasive lesions and invasive lesions of GGN lung adenocarcinoma. The lesion diameter can help to distinguish pre-invasive lesions and invasive lesions of GGN lung adenocarcinoma with different properties.